Proton Pump Inhibitor Use and Dental Implant Success

NCT ID: NCT06848855

Last Updated: 2025-02-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

54 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-11-01

Study Completion Date

2024-05-15

Brief Summary

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The goal of this observational study is to evaluate the effects of proton pump inhibitors (PPIs) on the surrounding bone and the survival of dental implants. The main questions it aims to answer are:

Does PPI use affect the survival rate of dental implants? Does PPI use influence crestal bone loss and fractal dimension (FD) of the surrounding bone?

Detailed Description

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Conditions

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Implant Survival Rate Implant Survival and Success

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Being over 18 years old,
* Having a history of PPI use for more than six months,
* Having at least one bone-level and axially placed dental implant in the maxilla or mandible,
* Having a minimum of one year elapsed since the prosthetic restoration following dental implant placement,
* Having undergone routine clinical follow-ups and radiological evaluations with periapical radiographs taken using the parallel cone technique after dental implant placement.

Exclusion Criteria

* Individuals with a history of PPI use for less than six months,
* Individuals with periapical radiographs of low image quality or with artifacts,
* Individuals for whom the regions selected for fractal analysis on periapical radiographs are not appropriately sized,
* Individuals who have not undergone routine clinical and radiographic follow-ups.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Berkay Tokuç

OTHER

Sponsor Role lead

Responsible Party

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Berkay Tokuç

Associate Professor

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Kocaeli University

Kocaeli, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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2023/295

Identifier Type: -

Identifier Source: org_study_id

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