Novel Method to Assess Hepatic Regeneration and Predict Hepatic Related Morbidity After Partial Hepatectomy

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

125 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-11-21

Study Completion Date

2039-01-01

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

the investigators will pursue two specific aims: (1) to monitor the extent of heme oxygenase induction (by measuring endogenous CO production) in relationship to the extent of hepatic resection (2) to assess the production of CO in patients following liver resection and correlate these findings to the rate of liver regeneration and liver function.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Postoperative Heme Oxygenase Induction and Carbon Monoxide Production as a Novel Method to Assess Hepatic Regeneration and Predict Hepatic Related Morbidity After Partial Hepatectomy

NCT04195438

Liver Cancer

COMPLETED NA

Factors Associated With End Stage Liver Disease

NCT01846819

Cirrhosis Hepatic Encephalopathy Fatigue +1 more

TERMINATED

Prospective, Observational Study of Biomarkers in Liver Cancer - Identification of Actionable Events

NCT01963949

Hepatocellular Carcinoma

WITHDRAWN

Transient Elastography in Hepatectomy for Hepatocellular Carcinoma

NCT01441453

Surgery Hepatocellular Carcinoma

UNKNOWN NA

Liver Regeneration After Liver Resection

NCT01220986

Liver Diseases Hepatectomy

UNKNOWN

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Liver Cancer Adult Liver Regeneration

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

all participants

all participants will provide breath samples to detect carbon monoxide levels

Group Type EXPERIMENTAL

carbon monoxide measurement via smokerlyzer

Intervention Type OTHER

participants in this study will provide breath samples for carbon monoxide measurements pre and post liver resection

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

carbon monoxide measurement via smokerlyzer

participants in this study will provide breath samples for carbon monoxide measurements pre and post liver resection

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Patient plans to have partial liver resection for primary liver pathology or metastatic disease
* Patient is able to comprehend and willing to sign the written consent form

Exclusion Criteria

* Patients \< 18 years
* Patients identified as members of a vulnerable population, except women of child bearing potential with negative pregnancy test

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No