Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
75 participants
OBSERVATIONAL
2022-01-01
2022-08-31
Brief Summary
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EVALUATION of GINGIVAL CREVICULAR FLUID and SERUM ASPROSIN LEVELS in OBESE and NORMAL-WEIGHT INDIVIDUALS with PERIODONTITIS
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Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
CROSS_SECTIONAL
Study Groups
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periodontal health group
Periodontal parameters were recorded at first visit and the fluid samples were collected from participants.
No interventions assigned to this group
Gingivitis group
Periodontal parameters were recorded at first visit and the fluid samples were collected from participants.
No interventions assigned to this group
periodontitis group
Periodontal parameters were recorded at first visit and the fluid samples were collected from participants.
No interventions assigned to this group
Eligibility Criteria
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Exclusion Criteria
* Individuals who take medication regularly
* Pregnant or lactating women
* Individuals with menopause and anthropause
* Those who have undergone any periodontal treatment in the last six months
* Smokers
18 Years
45 Years
ALL
Yes
Sponsors
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Mustafa Kemal University
OTHER
Responsible Party
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Osman Fatih Arpag
Principal investigator
Principal Investigators
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Abdulsamet Tanık, PhD
Role: STUDY_CHAIR
Adiyaman University
Locations
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Adiyaman University, Faculty of Dentistry
Adıyaman, , Turkey (Türkiye)
Countries
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References
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Shojaee M, Fereydooni Golpasha M, Maliji G, Bijani A, Aghajanpour Mir SM, Mousavi Kani SN. C - reactive protein levels in patients with periodontal disease and normal subjects. Int J Mol Cell Med. 2013 Summer;2(3):151-5.
Gul SNS, Eminoglu DO, Laloglu E, Aydin T, Dilsiz A. Salivary and serum asprosin hormone levels in the 2018 EFP/AAP classification of periodontitis stages and body mass index status: a case-control study. Clin Oral Investig. 2024 Jan 13;28(1):91. doi: 10.1007/s00784-024-05494-9.
de Molon RS, Rossa C Jr, Thurlings RM, Cirelli JA, Koenders MI. Linkage of Periodontitis and Rheumatoid Arthritis: Current Evidence and Potential Biological Interactions. Int J Mol Sci. 2019 Sep 13;20(18):4541. doi: 10.3390/ijms20184541.
Afacan B, Ozturk VO, Pasali C, Bozkurt E, Kose T, Emingil G. Gingival crevicular fluid and salivary HIF-1alpha, VEGF, and TNF-alpha levels in periodontal health and disease. J Periodontol. 2019 Jul;90(7):788-797. doi: 10.1002/JPER.18-0412. Epub 2018 Dec 11.
Tutus S, Tanik A, Arpag OF, Onderci M. Is there a relationship between periodontal conditions and asprosin levels in gingival crevicular fluid, saliva and serum? BMC Oral Health. 2025 Apr 29;25(1):651. doi: 10.1186/s12903-025-06014-1.
Other Identifiers
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DHFDUP/2022-0002
Identifier Type: -
Identifier Source: org_study_id
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