Effect of Transversus Thoracic Muscle Plane Block (TTMP) on Analgesia

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

46 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-08-01

Study Completion Date

2022-10-01

Brief Summary

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In this prospective and controlled study, the investigators investigated the effect of transversus thoracic muscle plane block (TTMP) on analgesia in patients who undergo coronary artery bypass graft (CABG) surgery with median sternotomy. For this purpose, the investigators aimed to compare the hemodynamic responses to surgical incision and sternotomy and, pain intensity, total analgesic consumption, additional analgesic requirements of the patients in the first 24 hours after extubation under postoperative patient-controlled analgesia (PCA) adminisration.

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Detailed Description

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Forty-six patients aged 18-70 years, ASA class I-III, who undergo CABG surgery were included in our study. The patients were randomized into the TTKPB group and the control group. Heart rate (HR) and mean arterial pressure (MAP) were recorded before peroperative induction, before skin incision, after skin incision, before sternotomy and after sternotomy. PCA with tramadol was applied after extubation and "Numeric rating scale" NRS scores, total tramadol consumption, number of requests and additional analgesic requirements were recorded at 0, 1, 2, 4, 8, 12 and 24 hours.

Conditions

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Coronary Artery Bypass Anesthesia, Conduction Nerve Block Pain, Postoperative

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Caregivers

Study Groups

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Transversus Thoracic Muscle Plane Block Group

Transversus thoracic muscle plane block is a single-shot nerve block technique that provides analgesia for the anterior chest wall

Group Type EXPERIMENTAL

Transversus Thoracic Muscle Plane Block

Intervention Type PROCEDURE

Transversus thoracic muscle plane block is a single-shot nerve block technique that provides analgesia for the anterior chest wall Tramadol IV PCA (Patient Controlled Analgesia): Basal infusion 0.2 mg/kg/h, bolus 20 mg, lock time 20 minutes

Tramadol

Intervention Type DRUG

Tramadol IV PCA (Patient Controlled Analgesia): Basal infusion 0.2 mg/kg/h, bolus 20 mg, lock time 20 minutes

Control Group

Group Type ACTIVE_COMPARATOR

Tramadol

Intervention Type DRUG

Tramadol IV PCA (Patient Controlled Analgesia): Basal infusion 0.2 mg/kg/h, bolus 20 mg, lock time 20 minutes

Interventions

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Transversus Thoracic Muscle Plane Block

Transversus thoracic muscle plane block is a single-shot nerve block technique that provides analgesia for the anterior chest wall Tramadol IV PCA (Patient Controlled Analgesia): Basal infusion 0.2 mg/kg/h, bolus 20 mg, lock time 20 minutes

Intervention Type PROCEDURE

Tramadol

Tramadol IV PCA (Patient Controlled Analgesia): Basal infusion 0.2 mg/kg/h, bolus 20 mg, lock time 20 minutes

Intervention Type DRUG

Other Intervention Names

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Tramadol

Eligibility Criteria

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Inclusion Criteria

* ASA (American Society of Anesthesiologists) classification I-III
* Coronary artery bypass graft operation with median sternotomy under elective conditions

Exclusion Criteria

* Refusing to participate in the study
* Under 18 and over 70
* ASA class IV and above
* EF (Ejection Fraction) \< 40%
* Emergency surgery or reoperation
* Intraaortic balloon pump placement
* Known allergy to local anesthetics
* Coagulation disorder
* Infection at the block site
* History of sternotomy
* Those with chronic pain complaints and long-term use of analgesics
* Patients who could not be extubated within 12 hours after the operation

Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No