Comparison of Tramadol, Pethidine and Morphine in the Treatment of Pain After Thoracic Surgery
NCT ID: NCT06172920
Last Updated: 2023-12-15
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
PHASE4
45 participants
INTERVENTIONAL
2023-12-31
2024-12-09
Brief Summary
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Detailed Description
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As a result of this pain caused by loss of tissue and pulmonary reserve, effective coughing and decreased chest expansion can lead to serious complications such as atelectasis, ventilation/perfusion mismatch, hypoxemia, immobilization, thromboembolism and infection. These complications are associated with increased morbidity and mortality in thoracic surgery (2).
Ensuring pain management in patients undergoing thoracotomy is important in terms of reducing postoperative complications, ensuring early mobilization and increasing patient comfort. Since there is no single source that causes pain after thoracotomy, pain must be controlled at all levels. For this reason, a multimodal approach using pharmacological and non-pharmacological techniques is preferred in analgesia after thoracotomy. This approach reduces drug side effects along with the consumption of analgesics. Opioids and nonsteroidal anti-inflammatory drugs are used in pharmacological analgesia.
In our study, the investigators aim to compare the effects of tramadol, pethidine and morphine using intravenous patient-controlled analgesia in the treatment of postoperative pain in elective thoracic surgery.
Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Tramadol
Tramadol receiving group
Tramadol hydrochloride
Patients are receiving tramadol hydrochloride under thoracic surgery
Aldolan
Aldolan receiving group
Aldolan
Patients are receiving meperidine under thoracic surgery
Morphine
Morphine receiving group
Morphine hydrochloride
Patients are receiving Morphine hydrochloride under thoracic surgery
Interventions
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Tramadol hydrochloride
Patients are receiving tramadol hydrochloride under thoracic surgery
Aldolan
Patients are receiving meperidine under thoracic surgery
Morphine hydrochloride
Patients are receiving Morphine hydrochloride under thoracic surgery
Eligibility Criteria
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Inclusion Criteria
* over 18 years old
* Being in group I-III according to the American Society of Anesthesiologists (ASA) classification
* Not have allergies to the drugs to be used (volunteers with diseases that prevent the use of drugs will not be included in the study
* regardless of gender
Exclusion Criteria
18 Years
90 Years
ALL
Yes
Sponsors
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Baskent University
OTHER
Responsible Party
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Begüm Nemika Gökdemir
Begüm Nemika Gökdemir, Research Assistant of Anesthesiology Department
Locations
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Baskent University Ankara Hospital
Ankara, , Turkey (Türkiye)
Countries
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Central Contacts
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Facility Contacts
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Adnan Torgay, Professor;MD
Role: primary
Other Identifiers
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KA23/137
Identifier Type: -
Identifier Source: org_study_id