Postoperative Effects of TAP Block Versus QLB Type 2 Block
NCT ID: NCT03126084
Last Updated: 2017-11-14
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE4
90 participants
INTERVENTIONAL
2017-05-02
2017-11-11
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
QUADRUPLE
Study Groups
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TAP
Patients will undergo inguinal hernia repair under subarachnoid block with 0.5% bupivacaine+glucose.
Patients will receive transversus abdominis plane block with 20 ml of 0.25% bupivacaine preoperatively, in addition to intravenous acetaminophen 1000mg twice a day for postoperative analgesia.
Tramadol HCl 50mg intramuscular will be provided for salvage analgesia postoperatively.
Acetaminophen
1000 mg of intravenous acetaminophen will be administered twice a day
0.25% Bupivacaine
20 ml of 0.25% bupivacaine will be administered to the fascia of the transversus abdominis muscle under ultrasound guidance.
0.5% Bupivacaine+Glucose
15mg of 0.5% bupivacaine will be administered to subarachnoid space through 25G spinal needle
Tramadol HCl
50mg of intramuscular tramadol will be administered when pain score is greater than 3 according to NRS
Inguinal Hernia Repair
Patients will undergo open inguinal hernia repair with one of the tension free mesh techniques
QLB2
Patients will undergo inguinal hernia repair under subarachnoid block with 0.5% bupivacaine+glucose.
Patients will receive quadratus lumborum type 2 block with 20 ml of %0.25 bupivacaine preoperatively, in addition to intravenous acetaminophen 1000mg twice a day for postoperative analgesia.
Tramadol HCl 50mg intramuscular will be provided for salvage analgesia postoperatively.
Acetaminophen
1000 mg of intravenous acetaminophen will be administered twice a day
0.5% Bupivacaine+Glucose
15mg of 0.5% bupivacaine will be administered to subarachnoid space through 25G spinal needle
Tramadol HCl
50mg of intramuscular tramadol will be administered when pain score is greater than 3 according to NRS
Inguinal Hernia Repair
Patients will undergo open inguinal hernia repair with one of the tension free mesh techniques
0.25% Bupivacaine
10 ml 0.25% bupivacaine will be administered quadratus lumborum muscle and erector spinae muscle
CONT
Patients will undergo inguinal hernia repair under subarachnoid block with 0.5% bupivacaine+glucose.
Patients will receive intravenous acetaminophen 1000mg twice a day for postoperative analgesia.
Tramadol HCl 50mg intramuscular will be provided for salvage analgesia postoperatively.
Acetaminophen
1000 mg of intravenous acetaminophen will be administered twice a day
0.5% Bupivacaine+Glucose
15mg of 0.5% bupivacaine will be administered to subarachnoid space through 25G spinal needle
Tramadol HCl
50mg of intramuscular tramadol will be administered when pain score is greater than 3 according to NRS
Inguinal Hernia Repair
Patients will undergo open inguinal hernia repair with one of the tension free mesh techniques
Interventions
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Acetaminophen
1000 mg of intravenous acetaminophen will be administered twice a day
0.25% Bupivacaine
20 ml of 0.25% bupivacaine will be administered to the fascia of the transversus abdominis muscle under ultrasound guidance.
0.5% Bupivacaine+Glucose
15mg of 0.5% bupivacaine will be administered to subarachnoid space through 25G spinal needle
Tramadol HCl
50mg of intramuscular tramadol will be administered when pain score is greater than 3 according to NRS
Inguinal Hernia Repair
Patients will undergo open inguinal hernia repair with one of the tension free mesh techniques
0.25% Bupivacaine
10 ml 0.25% bupivacaine will be administered quadratus lumborum muscle and erector spinae muscle
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Patients who are scheduled for elective unilateral open hernia repair with tension free mesh techniques
* Patients who are in ASA's physical status score group 1 or 2
Exclusion Criteria
* Patients who have severe stenotic heart diseases
* Patients who have bleeding diathesis
* Patients who have true allergies to local anesthetics
* Patients who have neurologic deficits corresponding to effect site of the anesthetic techniques
18 Years
ALL
No
Sponsors
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Bozyaka Training and Research Hospital
OTHER
Responsible Party
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Principal Investigators
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Zeki T TEKGUL, MD
Role: PRINCIPAL_INVESTIGATOR
Izmir Bozyaka Training and Research Hospital
Locations
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Izmir Bozyaka Training and Research Hospital
Izmir, , Turkey (Türkiye)
Countries
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References
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McDonnell JG, O'Donnell B, Curley G, Heffernan A, Power C, Laffey JG. The analgesic efficacy of transversus abdominis plane block after abdominal surgery: a prospective randomized controlled trial. Anesth Analg. 2007 Jan;104(1):193-7. doi: 10.1213/01.ane.0000250223.49963.0f.
Baerentzen F, Maschmann C, Jensen K, Belhage B, Hensler M, Borglum J. Ultrasound-guided nerve block for inguinal hernia repair: a randomized, controlled, double-blind study. Reg Anesth Pain Med. 2012 Sep-Oct;37(5):502-7. doi: 10.1097/AAP.0b013e31825a3c8a.
Finnerty O, Carney J, McDonnell JG. Trunk blocks for abdominal surgery. Anaesthesia. 2010 Apr;65 Suppl 1:76-83. doi: 10.1111/j.1365-2044.2009.06203.x.
Okur O, Karaduman D, Tekgul ZT, Koroglu N, Yildirim M. Posterior quadratus lumborum versus transversus abdominis plane block for inguinal hernia repair: a prospective randomized controlled study. Braz J Anesthesiol. 2021 Sep-Oct;71(5):505-510. doi: 10.1016/j.bjane.2020.11.004. Epub 2021 Feb 10.
Other Identifiers
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ANES-QLB-0609
Identifier Type: -
Identifier Source: org_study_id