Prediction of PaO2 Values Using the PRoPERLy II Database

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

8000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-01-01

Study Completion Date

2024-07-26

Brief Summary

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Four prospective observational studies of ventilation in critically ill patients were harmonized and pooled.

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Detailed Description

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The individual data from four observational studies ('Epidemiology of Respiratory Insufficiency in Critical Care study' \[ERICC\], the 'Large Observational Study to Understand the Global Impact of Severe Acute Respiratory Failure' \[LUNG SAFE\], 'PRactice of VENTilation in critically ill patients without ARDS' \[PRoVENT\], 'PRactice of VENTilation in critically ill patients in Middle-income Countries' \[PRoVENT-iMiC\]) were harmonized and pooled into a database named 'PRoPERLy II'. This database will be used to address various issues in diverse patient categories.

Conditions

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Invasive Ventilation

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Invasively ventilated intensive care unit patients.

Critically ill patients receiving invasive ventilation for various reasons, like ARDS, or AHRF.

Invasive ventilation.

Intervention Type OTHER

Patients were subjected to invasive ventilation.

Interventions

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Invasive ventilation.

Patients were subjected to invasive ventilation.

Intervention Type OTHER

Other Intervention Names

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Respiratory support.

Eligibility Criteria

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Exclusion Criteria

LUNG SAFE included patients aged 16 years or older that received invasive or noninvasive ventilation. LUNG SAFE excluded patients without informed consent. LUNG SAFE enrolled patients during a 4-week period in the winter months.

PRoVENT included patients aged 18 years or older that received invasive ventilation. PRoVENT excluded patients in whom ventilation was started before the study recruitment week, patients receiving only noninvasive ventilation, and patients that were transferred to the ICU from another hospital under ventilation. PRoVENT enrolled patients during 4-week period.

PRoVENT-iMiC included patients aged 18 years or older that started with invasive ventilation. They excluded patients that received only noninvasive ventilation, patients whose invasive ventilation started before the inclusion phase of the study, and patients transferred from another hospital while under ventilation. PRoVENT-iMiC enrolled patients during 4-week period.

Minimum Eligible Age

16 Years

Maximum Eligible Age

99 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No