Harmonized and Pooled Database, Named PRIME.

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

3270 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-01-01

Study Completion Date

2024-07-26

Brief Summary

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We merged the dataset of three large observational studies of invasive ventilation in critically ill patients.

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Detailed Description

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PRIME contains the individual patient data of 3 large observational studies of ventilation, 'PRactice of VENTilation in critically ill patients without ARDS' (PRoVENT), 'PRactice of VENTilation in critically ill patients in Middle-income Countries' (PRoVENT-iMiC) and 'Extubation strategies and in neuro-intensive care unit patients and associations with outcomes' (ENIO).

Conditions

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Invasive Ventilation

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Patients receiving invasive ventilation

Patients receiving invasive ventilation, included in PRoVENT, PRoVENT-iMiC, and ENIO

Invasive ventilation

Intervention Type OTHER

Invasive ventilation and respiratory support

Interventions

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Invasive ventilation

Invasive ventilation and respiratory support

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

All patients in the PRIME database are eligible for participation in the initial analysis presented here. We will exclude patients receiving ventilation fir another reason than acute brain injury.

Minimum Eligible Age

18 Years

Maximum Eligible Age

99 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No