Delineation of Target Volume of Stereotactic Radiotherapy for Spinal Tumors

NCT ID: NCT06587022

Last Updated: 2024-09-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-01-01

Study Completion Date

2027-12-30

Brief Summary

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The purpose of this study was to compare efficacy and side effects of two target delineation methods for stereotactic radiotherapy of metastatic spinal tumors.

Detailed Description

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The purpose of this study was to compare efficacy and side effects of two target delineation methods for stereotactic radiotherapy of metastatic spinal tumors. This is a bidirectional cohort study planned to enroll approximately 500 patients with metastatic spinal tumors. Patients are divided into two groups according to the target delineation method. Group 1:The target bolume only includes local tumor. Group 2:The target bolume includes local tumor and adjacent vertebral area.

Conditions

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Spinal Tumor

Study Design

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Observational Model Type

COHORT

Study Time Perspective

OTHER

Study Groups

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group 1

Group 1(small target delineation):The target bolume only includes local tumor.

Target volume delineation

Intervention Type RADIATION

Group 1(small target delineation):The target bolume only includes local tumor. Group 2(small target delineation):The target bolume includes local tumor and adjacent vertebral area.

group 2

Group 2(small target delineation):The target bolume includes local tumor and adjacent vertebral area.

Target volume delineation

Intervention Type RADIATION

Group 1(small target delineation):The target bolume only includes local tumor. Group 2(small target delineation):The target bolume includes local tumor and adjacent vertebral area.

Interventions

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Target volume delineation

Group 1(small target delineation):The target bolume only includes local tumor. Group 2(small target delineation):The target bolume includes local tumor and adjacent vertebral area.

Intervention Type RADIATION

Eligibility Criteria

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Inclusion Criteria

* Patients with spinal metastases or primary tumors receiving stereotactic radiotherapy;
* Patients with sufficent pre-treatment imaging data
* Patients who can cooperate with imaging review and follow-up after radiotherapy.

Exclusion Criteria

* Patients with an expected survival of less than 3 months;
* Patients with second-course radiotherapy;
* Patients with physical conditions that cannot tolerate stereotactic radiotherapy;
* Patients with extensive spinal metastasis and no local therapeutic value
Minimum Eligible Age

18 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Peking University Third Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Hongqing Zhuang

Role: STUDY_DIRECTOR

Peking University Third Hospital

Locations

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Department of Radiation Oncology Cancer Center, Peking University Third Hospital 49# North Garden Rd.,Haidian Dist.

Beijing, Beijing Municipality, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Hongqing Zhuang, Doctor

Role: CONTACT

13051776232

Yuxia Wang

Role: CONTACT

15001292991

Facility Contacts

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Hongqing Zhuang

Role: primary

13051776232

Other Identifiers

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ST-SBRT

Identifier Type: -

Identifier Source: org_study_id

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