High-intensity Interval Circuit Training in People With Parkinson Disease

NCT ID: NCT06576817

Last Updated: 2025-01-20

Basic Information

• Recruitment Status: RECRUITING
• Clinical Phase: NA
• Total Enrollment: 64 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2024-02-15
• Study Completion Date: 2026-08-31

Brief Summary

The goal of the study is to compare different types of high intensity circuit exercises over an 8-class training series in people with Parkinson disease. The main question it aims to answer is:

-Does including arm and hand exercises with leg exercises improve reaction time, balance, functional measures, gait speed and quality of life? This group will be compared to a group that only does leg exercises. Participants will be asked to participate in 8 high intensity circuit exercise classes.

Detailed Description

People with Parkinson disease will be recruited from the community and randomized into 2 equal groups: high intensity interval circuit training with lower extremity (LE) and lower and upper extremity (LEUE) training. The study will be composed of a baseline assessment, 8 group class sessions, and a post-intervention assessment. The baseline assessment will include demographics, disease and fall history and outcome measure collection. Group class sessions will include concurrent group warmup, followed by an 8-station circuit performed with high intensity intervals, and a cool-down. The circuit will include 4 stations performed by both the LE and LEUE groups and 4 stations specific to each intervention group, including 4 additional LE exercise stations for the LE group and 4 UE specific stations for the LEUE group. The stations that differ will not be adjacent to one another nor specifically indicated as different. The stations that differ will mirror similar aspects of function (ie, strength, reaction time, etc.) for the UE and LE stations. Participants will be told exercise stations may vary within-session and week to week but will not be informed that only one group has UE exercise interventions. After conclusion of the class series, post-intervention balance and stepping outcomes will be reassessed.

Conditions

Parkinson Disease

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: DOUBLE

Study Groups

Lower extremity and upper extremity exercise

Exercises in the circuit (8 total) will focus on the lower extremity (4) and upper extremity (4)

Group Type: EXPERIMENTAL

High intensity circuit exercise class - Lower and upper extremity

Intervention Type: OTHER

Exercises performed at high intensity effort in the circuit (8 total) will focus on both the lower extremity (4) and upper extremity (4)

Lower extremity exercise

Exercises in the circuit (8 total) will focus on the lower extremity (4) alone.

Group Type: ACTIVE_COMPARATOR

High intensity circuit exercise class - Lower extremity alone

Intervention Type: OTHER

All exercises performed at high intensity effort in the circuit (8 total) will focus on the lower extremity alone

Interventions

High intensity circuit exercise class - Lower and upper extremity

Exercises performed at high intensity effort in the circuit (8 total) will focus on both the lower extremity (4) and upper extremity (4)

Intervention Type: OTHER

High intensity circuit exercise class - Lower extremity alone

All exercises performed at high intensity effort in the circuit (8 total) will focus on the lower extremity alone

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• diagnosis of Parkinson's disease
• Hoehn and Yahr level of 1 to 3
• ability to walk independently with or without an assistive device
• obtain medical clearance to participate in moderate or vigorous exercise.

Exclusion Criteria

• diagnosis of any neurological disease other than PD (including but not limited to stroke, dementia, and multiple sclerosis; mild cognitive impairment is not excluded)
• bone instability (non-consolidated fractures, unstable spinal column, severe osteoporosis)
• muscle or ligament tears
• uncontrolled hypertension
• uncontrolled diabetes
• severe cardiovascular disease that impairs walking or exercise
• a major change in medication during the study training period (pre-test to post-test)

• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Pacific Northwest University of Health Sciences

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Tiffany B Salido, DPT, PhD

Role: PRINCIPAL_INVESTIGATOR

Pacific Northwest University of Health Sciences

Locations

Pacific Northwest University of Health Sciences

Yakima, Washington, United States

Site Status: RECRUITING

Countries

United States

Central Contacts

Tiffany B Salido, DPT, PhD

Role: CONTACT

tsalido@pnwu.edu

509-249-7920

Ron Walser, PT, DPT

Role: CONTACT

rwalser@pnwu.edu

509-249-7895

Facility Contacts

Tiffany B Salido, DPT, PhD

Role: primary

tsalido@pnwu.edu

509-249-7920

Other Identifiers

24-003

Identifier Type: -

Identifier Source: org_study_id