Effect of Prone Positionning in Non Intubated Patients

NCT ID: NCT06517745

Last Updated: 2024-07-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

114 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-01-01

Study Completion Date

2021-10-30

Brief Summary

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Retrospective single center study on the effect of awake prone positioning in ICU patients with severe hypoxemia related to SARS-COV2

Detailed Description

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Retrospective, observational study on the effects of awake prone positioning on oxygenation, invasive mechanical ventilation requirement and mortality in non intubation patients with severe hypoxemia related to SARS-COV2 and regardeless of the oxygen supplementation method.

Conditions

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SARS-CoV 2 Pneumonia Acute Respiratory Distress Syndrome Prone Positioning

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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Prone position group

Prone positioning sessions: at least 1 session per day session duration: at least 2 hours

Prone positioning

Intervention Type PROCEDURE

Prone positioning sessions: at least one session per day proning duration: 2 hours at least per session

Control group

no prone positioning

No interventions assigned to this group

Interventions

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Prone positioning

Prone positioning sessions: at least one session per day proning duration: 2 hours at least per session

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* All adult (\> 18 years) patients, non intubated, with acute respiratory failure due to COVID-19 pulmonary infection

Exclusion Criteria

* patients: hemodynamic instability and high doses of vasopressors
* patients with contraindications of prone positioning: pregnancy, recent abdominal surgery
* patients with pulmonay embolism
* patients requiring invasive mechanical ventilation for extra respiratory reasons: neurological failure, urgent surgery
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Mongi Slim Hospital

OTHER

Sponsor Role lead

Responsible Party

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Mhamed Sami Mebazaa

Professor head of Anesthesiology and ICU department

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Mongi Slim hospital

Tunis, , Tunisia

Site Status

Countries

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Tunisia

Other Identifiers

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COVID PP

Identifier Type: -

Identifier Source: org_study_id

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