" Role of Diffusion Weighted Image in the Diagnosis and Follow up of Breast Cancer"
NCT ID: NCT06494865
Last Updated: 2024-08-07
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
30 participants
OBSERVATIONAL
2024-08-01
2024-12-01
Brief Summary
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Detailed Description
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Nowadays sonomammography still represents the primary imaging modality utilized for breast cancer screening and diagnosis.
Breast MRI has become an important tool for breast cancer detection and characterization.Contrast enhanced MRI(CE-MRI) is currently the most sensitive detection technique for diagnosis of breast cancer.Diffusion weighted imaging provides micro-structural informations regadrding the diffusion of the water molecules in the tissue cellularity and tissue structure by using the quantitive analysis with the apparent diffusion coefficient (ADC) values.
Using Diffusion weighted imaging (DWI) combined to MRI is helpful to distinguish malignant versus benign breast lesions and it also may reduce the number of unnecessarily breast biopsies.
Conditions
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Study Design
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CASE_ONLY
CROSS_SECTIONAL
Interventions
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MRI device
Standered breast coils with small field of veiw and thin sections will be used for the examinatio.
MRI breast including Axial T1WI, T2WI Stir contrast DWI and Stir sagittal T1WI with contrast traction and subtraction
Eligibility Criteria
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Inclusion Criteria
* Age more than 18 years
* Patients presented with breast lump
* Patients with recurrent breast cancer following chemotherapy or radiotherapy sessions.
Exclusion Criteria
* Age younger than 18 years
* Patients with recent breast trauma in the same diseased breast within the last 6 months
* Lactating female presented with acute symptoms as trauma or breast abscess
* Contraindication to perform MRI examination .these include : Cardiac pacemaker -Metallic aneurysm clips
18 Years
70 Years
FEMALE
No
Sponsors
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Sohag University
OTHER
Responsible Party
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Mennatallah Ashraf Ibrahim
Resident-radiology department-sohag hospital university
Central Contacts
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Medhat I Mohammed, professor
Role: CONTACT
References
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Stachs A, Stubert J, Reimer T, Hartmann S. Benign Breast Disease in Women. Dtsch Arztebl Int. 2019 Aug 9;116(33-34):565-574. doi: 10.3238/arztebl.2019.0565.
Butti R, Das S, Gunasekaran VP, Yadav AS, Kumar D, Kundu GC. Receptor tyrosine kinases (RTKs) in breast cancer: signaling, therapeutic implications and challenges. Mol Cancer. 2018 Feb 19;17(1):34. doi: 10.1186/s12943-018-0797-x.
Shi RY, Yao QY, Wu LM, Xu JR. Breast Lesions: Diagnosis Using Diffusion Weighted Imaging at 1.5T and 3.0T-Systematic Review and Meta-analysis. Clin Breast Cancer. 2018 Jun;18(3):e305-e320. doi: 10.1016/j.clbc.2017.06.011. Epub 2017 Jul 5.
Yilmaz E, Sari O, Yilmaz A, Ucar N, Aslan A, Inan I, Parlakkilic UT. Diffusion-Weighted Imaging for the Discrimination of Benign and Malignant Breast Masses; Utility of ADC and Relative ADC. J Belg Soc Radiol. 2018 Feb 7;102(1):24. doi: 10.5334/jbsr.1258.
Other Identifiers
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soh-Med-24-06-23MS
Identifier Type: -
Identifier Source: org_study_id
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