Use of Compressed Sensing in Breast MRI

NCT ID: NCT02826369

Last Updated: 2018-08-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

13 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-03-29

Study Completion Date

2016-04-12

Brief Summary

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Breast MRI is increasingly important in breast screening imaging. It is currently based on dynamic sequences after contrast injection whose temporal resolution must be less than 90 seconds with dynamic acquisitions at different times.

These curves profiles are designed to differentiate benign from malignant lesions. Recently, Mann et al, (2014) showed that increasing the temporal resolution of dynamic acquisitions; lesion enhancement curves over time were more accurate than the curves usually performed.

It seems necessary to work on sequences having better temporal resolution without compromising however spatial resolution.

Detailed Description

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Conditions

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Breast Cancer

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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3.0 Tesla in Magnetic Resonance Imaging

Group Type EXPERIMENTAL

3.0 Tesla in Magnetic Resonance Imaging

Intervention Type OTHER

Eligible patient will have a standard MRI. The images taken before 4min30 and after 6min after to the injection of gadolimium contrast medium will be carried out with the standard image acquisition.

The images taken between 4min30 and 6min after the injection of gadolimium contrast medium will be carried out with the compressed sensing image acquisition.

Interventions

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3.0 Tesla in Magnetic Resonance Imaging

Eligible patient will have a standard MRI. The images taken before 4min30 and after 6min after to the injection of gadolimium contrast medium will be carried out with the standard image acquisition.

The images taken between 4min30 and 6min after the injection of gadolimium contrast medium will be carried out with the compressed sensing image acquisition.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patient to benefit a MRI in the assessment for a breast carcinoma
* Age \>18 years old
* Assessment on 3.0 Tesla in Magnetic Resonance Imaging
* ECOG performance status ≤ 3
* Ability to provide an informed written consent form

Exclusion Criteria

* Age \< 18 years old
* Claustrophobia
* Contraindication to the injection of gadolinium contrast medium
* Contraindication to MRI
* Persons deprived of liberty or under supervision
Maximum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Institut de Cancérologie de Lorraine

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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OLDRINI Guillaume, MD

Role: PRINCIPAL_INVESTIGATOR

Institut de Cancérologie de Lorraine

Locations

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Institut de Cancérologie de Lorraine

Vandœuvre-lès-Nancy, , France

Site Status

Countries

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France

Other Identifiers

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2015-A00581-48

Identifier Type: -

Identifier Source: org_study_id

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