Stroke Rehabilitation: A Systemized and Hierarchized Rehabilitation Program for the Brazilian Unified Health System

NCT ID: NCT06494202

Last Updated: 2024-07-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-10-01

Study Completion Date

2026-12-31

Brief Summary

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The goal of this clinical trial is to systemize and hierarchize a rehabilitation program for the Brazilian Unified Health System in patients with stroke above 18 years of age and of both sexes. The main question it aims to answer is:

* Do patients with ischemic first episode of stroke have central nervous systems consequences due to peripheral and central nervous system sensibilization?
* Can stroke patients benefit from a systemized and hierarchized rehabilitation program with desensibilization interventions combined with multidisciplinary and educational programs?

We will randomize 60 patients, 30 in each study arm.

Researchers will compare the intervention group with an active control whose treatment is the institutional conventional program to see if innovative desensibilization strategies yield superior results. Authors will also investigate the role of genetic polymorphism and ancestrality in the outcome measures.

Participants will undertake an innovative or conventional rehabilitation program, according to the randomization.

Detailed Description

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Conditions

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Stroke, Ischemic

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

DOUBLE

Caregivers Outcome Assessors
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Study Groups

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Conventional rehabilitation program

Conventional rehabilitation intervention with multidisciplinary team (medical services, physiotherapy, occupational therapy, physical education, psychology, nutrition, social service, speech therapy, and nurse) delivered during four to six weeks of intensive in-patient program

Group Type ACTIVE_COMPARATOR

Conventional rehabilitation program.

Intervention Type OTHER

Conventional rehabilitation program

Innovative rehabilitation program

Conventional rehabilitation intervention with multidisciplinary team (medical services, physiotherapy, occupational therapy, physical education, psychology, nutrition, social service, speech therapy, and nurse) delivered during four to six weeks of intensive in-patient program combined with innovative medical therapies (laser therapy, radial extracorporeal shockwaves therapy, focused extracorporeal shockwaves therapy, segmentary desensibilization with lidocaine, functional electrical stimulation - FES).

Group Type EXPERIMENTAL

Innovative rehabilitation

Intervention Type OTHER

Conventional rehabilitation program associated with innovative therapies.

Conventional rehabilitation program.

Intervention Type OTHER

Conventional rehabilitation program

Interventions

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Innovative rehabilitation

Conventional rehabilitation program associated with innovative therapies.

Intervention Type OTHER

Conventional rehabilitation program.

Conventional rehabilitation program

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Clinical and radiological (magnetic resonance or tomography) diagnosis of ischemic stroke;
* Single episode of stroke;
* Clinical stability according to medical assessment;
* Time since stroke onset no longer than 24 months;
* Capacity to understand the study procedures;
* Eligible to be admitted to hospitalization at the institute where the study will be conducted
* Agree to sign the Informed Consent Form (ICF).

Exclusion Criteria

* Presence of psychiatric disorders;
* Presence of subarachnoid hemorrhage;
* Presence of intracerebral hemorrhage;
* Presence of neuromuscular disorders;
* Presence of other neurological diseases or brain neoplasm;
* Presence of cognitive disorders measured with Montreal Cognitive Assessment (MoCA), scores below 20 points;
* Presence of systemic arterial hypertension (systolic blood pressure ≥ 185mmHg or diastolic blood pressure ≥ 110 mmHg).
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Ministry of Health, Brazil

OTHER_GOV

Sponsor Role collaborator

University of Sao Paulo

OTHER

Sponsor Role lead

Responsible Party

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Marta Imamura

MD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Marta Imamura, Professor

Role: PRINCIPAL_INVESTIGATOR

Instituto de Medicina Física e Reabilitação - FMUSP

Locations

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Instituto de Medicina Física e Reabilitação (IMREA-FMUSP)

São Paulo, , Brazil

Site Status

Countries

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Brazil

Central Contacts

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Marta Imamura, Professor

Role: CONTACT

55-11-5180-8017

Artur Santos

Role: CONTACT

55-11-5180-8017

Other Identifiers

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78062224.5.0000.0068

Identifier Type: -

Identifier Source: org_study_id

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