Effectiveness of Intelligent Rehabilitation Robot Training System Combined With Repetitive Facilitative Exercise on Upper Limb Motor Function After Stroke: a Randomized Control Trial.

NCT ID: NCT06435624

Last Updated: 2025-03-05

Study Results

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

81 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-06-15

Study Completion Date

2024-08-31

Brief Summary

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The goal of this clinical trial is to learn if intelligent rehabilitation robot training system combined with repetitive facilitative exercise (RFE) work to treat stroke in adults. The main questions it aims to answer are:

Does drug intelligent rehabilitation robot training system combined with RFE improve the upper limb motor function of participants? Can the combination of intelligent rehabilitation robot training system and RFE achieve better effects?

Researchers will compare 3 groups (RFE, intelligent rehabilitation robot training system under RFE, and conventional therapy) to see if intelligent rehabilitation robot training system and RFE works to treat stroke.

Participants will:

Receive treatment for 4 weeks Receive scale and instrument testing before and after treatment

Detailed Description

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Conditions

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Stroke

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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IRAT group

The Intelligent robotic-assisted training (IRAT) group received a 30 minute RFE intervention and a 30 minute IRAT intervention.

Group Type EXPERIMENTAL

intelligent robotic-assisted training

Intervention Type DEVICE

Using an intelligent robotic-assisted training (IRAT) system to simulate a real work environment, providing functional oriented treatment for stroke patients and improving upper limb motor function.

The instrument used is the Burt upper limb robot training system produced by Estun Medical Co., Ltd.

repetitive facilitative exercise

Intervention Type OTHER

Repetitive facilitative exercise (RFE) is a new technology that combines multiple sensory stimuli and achieves facilitation and reinforcement of the reconstruction of paralyzed neural pathways through repeated and extensive directional exercise.

RFE group

The Repetitive facilitative exercise (RFE) group received a 60 minute RFE intervention.

Group Type ACTIVE_COMPARATOR

repetitive facilitative exercise

Intervention Type OTHER

Repetitive facilitative exercise (RFE) is a new technology that combines multiple sensory stimuli and achieves facilitation and reinforcement of the reconstruction of paralyzed neural pathways through repeated and extensive directional exercise.

CT group

The Conventional therapy (CT) group received a 60 minute conventional rehabilitation intervention.

Group Type ACTIVE_COMPARATOR

conventional therapy

Intervention Type OTHER

Basic training, including passive joint movement and activities of daily living exercise.

Interventions

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intelligent robotic-assisted training

Using an intelligent robotic-assisted training (IRAT) system to simulate a real work environment, providing functional oriented treatment for stroke patients and improving upper limb motor function.

The instrument used is the Burt upper limb robot training system produced by Estun Medical Co., Ltd.

Intervention Type DEVICE

repetitive facilitative exercise

Repetitive facilitative exercise (RFE) is a new technology that combines multiple sensory stimuli and achieves facilitation and reinforcement of the reconstruction of paralyzed neural pathways through repeated and extensive directional exercise.

Intervention Type OTHER

conventional therapy

Basic training, including passive joint movement and activities of daily living exercise.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* patients (18 to 74 years old) who suffered a first or second unilateral stroke
* chronic stroke (over 6 months from the onset)
* obvious upper limb movement disorders (FMA-UE scores from 25 to 42)
* ability to understand and follow simple directions

Exclusion Criteria

* pregnant or lactating
* upper extremity contracture, pain, or trauma
* perceptual, apraxic, or cognitive deficits that lead to inability to follow verbal instructions
* unable to maintain sitting posture
* cerebellar lesion
* clinically unstable medical disorders
* inability to provide informed consent
Minimum Eligible Age

18 Years

Maximum Eligible Age

74 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Nanjing Mingzhou Rehabilitation Hospital

OTHER

Sponsor Role lead

Responsible Party

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Jingzhi Zhang

technician

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Nanjing Mingzhou Rehabilitation Hospital

Nanjing, Jiangsu, China

Site Status

Countries

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China

References

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Zhang JZ, Chen J, Liu XL, Yan LB, Xu SM. Effectiveness of intelligent robotic-assisted training system combined with repetitive facilitative exercise on upper limb motor function after stroke: a randomized controlled trial. BMC Sports Sci Med Rehabil. 2025 Jul 3;17(1):178. doi: 10.1186/s13102-025-01234-y.

Reference Type DERIVED
PMID: 40611355 (View on PubMed)

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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NJKF202401001

Identifier Type: -

Identifier Source: org_study_id

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