Comparison of Oral Isotretinoin vs Ancomparison of Oral Isotretinoin vs Antibiotics on Corneal Thickness With AV

NCT ID: NCT06483971

Last Updated: 2024-07-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

36 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-11-01

Study Completion Date

2024-10-30

Brief Summary

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Comparison of Oral Isotretinoin versus comparison of Oral Isotretinoin versus Antibiotics on Corneal Thickness in Patients with Acne Vulgaris

Detailed Description

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Acne is the most common skin disease requiring attention of health practitioners. It is a self-limiting disease of the pilosebaceous unit, which can lead to devastating and frustrating scars and pigmentary alterations.

Conditions

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Cornea

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

NONE

Study Groups

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Oral Isotretinoin

Group Type OTHER

Oral Isotretinoin

Intervention Type DIAGNOSTIC_TEST

20 mg/kg/day that affects sebaceous glands and is used to treat severe acne Frequency: Once daily

Antibiotics

Group Type EXPERIMENTAL

Antibiotics

Intervention Type COMBINATION_PRODUCT

250 mg on laternate day/3 months Frequency: Once or twice daily

Interventions

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Oral Isotretinoin

20 mg/kg/day that affects sebaceous glands and is used to treat severe acne Frequency: Once daily

Intervention Type DIAGNOSTIC_TEST

Antibiotics

250 mg on laternate day/3 months Frequency: Once or twice daily

Intervention Type COMBINATION_PRODUCT

Eligibility Criteria

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Inclusion Criteria

* Patients of either gender shall be enrolled for this study.
* Acne vulgaris patients taking oral isotretinoin and oral antibiotics shall be included.

Exclusion Criteria

* Patients with any ocular pathology shall be excluded.
* Patients with any systemic pathology other than acne vulgaris shall be excluded.
* Patients with history of contact lens wear, previous refractive surgery or injury shall be excluded.
Minimum Eligible Age

20 Years

Maximum Eligible Age

43 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Superior University

OTHER

Sponsor Role lead

Responsible Party

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Muhammad Naveed Babur

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Shalamar Hospital Mughalpura

Lahore, Punjab Province, Pakistan

Site Status

Countries

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Pakistan

Other Identifiers

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MSRSW/Batch-Fall22/731

Identifier Type: -

Identifier Source: org_study_id

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