Applied Forces During Neonatal Intubation at Different Heights of the Resuscitation Table

NCT ID: NCT06474572

Last Updated: 2024-06-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

32 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-06-30

Study Completion Date

2024-06-30

Brief Summary

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The study aims to compare the applied forces during intubation of a newborn manikin with direct and video laryngoscope at different heights of the resuscitation table. Furthermore, the success at the first attempt, the intubation time and participants' opinion on the procedures were investigated.

This is an unblinded, randomized, controlled, crossover trial on the applied forces during intubation of a newborn manikin with direct and video laryngoscope at different heights of the resuscitation table.

Detailed Description

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Background: Endotracheal intubation is an important life-saving procedure for critically ill neonates. Some procedure-related aspects may affect the quality of the intubation. Optimizing the relative height between patient and operator may improve intubation procedures.

Objectives: To compare the applied forces during intubation of a newborn manikin with direct and video laryngoscope at different heights of the resuscitation table. Furthermore, the success at the first attempt, the intubation time, and participants' opinions on the procedures were investigated.

Methods: This is an unblinded, randomized, controlled, crossover trial on the applied forces during intubation of a newborn manikin with direct and video laryngoscope at different heights of the resuscitation table. Participants will be Level III NICU/PICU consultants, and pediatric residents. Randomization will be performed using a computer-generated random assignment list. The primary outcome measure will be the forces applied on the neonatal manikin during the intubation. The secondary outcome measures will be the success of the first attempt, the total time of intubation, and participants' opinions about the procedure.

Conditions

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Neonatal Disease Intubation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Direct laryngoscope and table at xiphoid level

Participants will be required to intubate the manikin with a direct laryngoscope and table at xiphoid level

Group Type ACTIVE_COMPARATOR

Direct laryngoscope and table at xiphoid level

Intervention Type DEVICE

Participants will be required to intubate the manikin with a direct laryngoscope and table at xiphoid level

Videolaryngoscope and table at xiphoid level

Participants will be required to intubate the manikin with a video laryngoscope and table at xiphoid level

Group Type ACTIVE_COMPARATOR

Videolaryngoscope and table at xiphoid level

Intervention Type DEVICE

Participants will be required to intubate the manikin with a video laryngoscope and table at xiphoid level

Direct laryngoscope and table at umbilical level

Participants will be required to intubate the manikin with a direct laryngoscope and table at umbilical level

Group Type ACTIVE_COMPARATOR

Direct laryngoscope and table at umbilical level

Intervention Type DEVICE

Participants will be required to intubate the manikin with a direct laryngoscope and table at umbilical level

Videolaryngoscope and table at umbilical level

Participants will be required to intubate the manikin with a video laryngoscope and table at umbilical level

Group Type EXPERIMENTAL

Videolaryngoscope and table at umbilical level

Intervention Type DEVICE

Participants will be required to intubate the manikin with a videolaryngoscope and table at umbilical level

Interventions

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Direct laryngoscope and table at xiphoid level

Participants will be required to intubate the manikin with a direct laryngoscope and table at xiphoid level

Intervention Type DEVICE

Videolaryngoscope and table at xiphoid level

Participants will be required to intubate the manikin with a video laryngoscope and table at xiphoid level

Intervention Type DEVICE

Direct laryngoscope and table at umbilical level

Participants will be required to intubate the manikin with a direct laryngoscope and table at umbilical level

Intervention Type DEVICE

Videolaryngoscope and table at umbilical level

Participants will be required to intubate the manikin with a videolaryngoscope and table at umbilical level

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Level III NICU and PICU consultants, and pediatric residents

Exclusion Criteria

* Refusal to participate
Minimum Eligible Age

25 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University Hospital Padova

OTHER

Sponsor Role lead

Responsible Party

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Daniele Trevisanuto

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Central Contacts

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Daniele Trevisanuto, MD

Role: CONTACT

0498211489

References

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Evans P, Shults J, Weinberg DD, Napolitano N, Ades A, Johnston L, Levit O, Brei B, Krick J, Sawyer T, Glass K, Wile M, Hollenberg J, Rumpel J, Moussa A, Verreault A, Abou Mehrem A, Howlett A, McKanna J, Nishisaki A, Foglia EE. Intubation Competence During Neonatal Fellowship Training. Pediatrics. 2021 Jul;148(1):e2020036145. doi: 10.1542/peds.2020-036145. Epub 2021 Jun 25.

Reference Type BACKGROUND
PMID: 34172556 (View on PubMed)

Pouppirt NR, Nassar R, Napolitano N, Nawab U, Nishisaki A, Nadkarni V, Ades A, Foglia EE. Association Between Video Laryngoscopy and Adverse Tracheal Intubation-Associated Events in the Neonatal Intensive Care Unit. J Pediatr. 2018 Oct;201:281-284.e1. doi: 10.1016/j.jpeds.2018.05.046. Epub 2018 Jul 3.

Reference Type BACKGROUND
PMID: 29980290 (View on PubMed)

Geraghty LE, Dunne EA, Ni Chathasaigh CM, Vellinga A, Adams NC, O'Currain EM, McCarthy LK, O'Donnell CPF. Video versus Direct Laryngoscopy for Urgent Intubation of Newborn Infants. N Engl J Med. 2024 May 30;390(20):1885-1894. doi: 10.1056/NEJMoa2402785. Epub 2024 May 5.

Reference Type BACKGROUND
PMID: 38709215 (View on PubMed)

Xue FS, Li RP, Liu GP. Dynamic optimization of height relation between anaesthetist's chest and patient's face during tracheal intubation. Br J Anaesth. 2015 Feb;114(2):348-9. doi: 10.1093/bja/aeu479. No abstract available.

Reference Type BACKGROUND
PMID: 25596228 (View on PubMed)

Gordon JK, Bertram VE, Cavallin F, Parotto M, Cooper RM. Direct versus indirect laryngoscopy using a Macintosh video laryngoscope: a mannequin study comparing applied forces. Can J Anaesth. 2020 May;67(5):515-520. doi: 10.1007/s12630-020-01583-x. Epub 2020 Mar 9.

Reference Type BACKGROUND
PMID: 32152886 (View on PubMed)

Other Identifiers

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NEOUNIPD5(2024)

Identifier Type: -

Identifier Source: org_study_id

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