Shengyu Decoction and Lijin Manipulation for Knee OA: 3D Gait Analysis
NCT ID: NCT06451783
Last Updated: 2024-06-11
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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ENROLLING_BY_INVITATION
EARLY_PHASE1
94 participants
INTERVENTIONAL
2024-05-01
2025-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
TRIPLE
Study Groups
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Combined treatment group
Traditional Chinese medicine combined with manipulation treatment：the Shengyu Decoction, which consists of the following herbs:
* Shu Di Huang 20 grams
* Bai Shao 15 grams
* Dang Gui 15 grams
* Chuan Xiong 8 grams
* Ren Shen 20 grams
* Huang Qi 18 grams One dose is taken per day, and a course of treatment consists of five weeks.
Traditional Chinese medicine combined with manipulation treatment
The specific procedure involves administering the Shengyu Decoction, which consists of the following herbs:
* Shu Di Huang 20 grams
* Bai Shao 15 grams
* Dang Gui 15 grams
* Chuan Xiong 8 grams
* Ren Shen 20 grams
* Huang Qi 18 grams One dose is taken per day, and a course of treatment consists of five weeks. Add manipulation of massage：
* Press and grasp the affected limb three times；
* Five-finger five-acupoint pressing method；
* Point pressing on Zusanli (ST36) and Sanyinjiao (SP6)；
* grasp the interior method to treat the calf three times；
⑤ Apply rolling technique around the knee joint；
⑥ Knead and straighten the standing tendon (the lateral muscle of the calf)；
⑦ Six-finger six-acupoint pressing method；
⑧ Push and pull the patella to flex and extend the knee joint；
⑨ Knee joint reunion and smooth dispersion method.
Control group
Oral control group medication： Oral Celecoxib Capsules, 200mg per dose, once daily after lunch.
Celecoxib capsule
Oral Celecoxib Capsules, 200mg per dose, once daily after lunch.
Interventions
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Traditional Chinese medicine combined with manipulation treatment
The specific procedure involves administering the Shengyu Decoction, which consists of the following herbs:
* Shu Di Huang 20 grams
* Bai Shao 15 grams
* Dang Gui 15 grams
* Chuan Xiong 8 grams
* Ren Shen 20 grams
* Huang Qi 18 grams One dose is taken per day, and a course of treatment consists of five weeks. Add manipulation of massage：
* Press and grasp the affected limb three times；
* Five-finger five-acupoint pressing method；
* Point pressing on Zusanli (ST36) and Sanyinjiao (SP6)；
* grasp the interior method to treat the calf three times；
⑤ Apply rolling technique around the knee joint；
⑥ Knead and straighten the standing tendon (the lateral muscle of the calf)；
⑦ Six-finger six-acupoint pressing method；
⑧ Push and pull the patella to flex and extend the knee joint；
⑨ Knee joint reunion and smooth dispersion method.
Celecoxib capsule
Oral Celecoxib Capsules, 200mg per dose, once daily after lunch.
Eligibility Criteria
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Inclusion Criteria
* TCM diagnostic criteria: Dull pain in the knee joint, flexion and extension limitations, pitching and side rotation unfavorability, slight activities slightly relieve pain, climate change aggravates symptoms, and repeated middle-aged and elderly patients, hidden onset, slow onset, slight local swelling of the knee joint, friction or clicking sound when moving, and severe cases may show muscle atrophy and joint deformity.
* Radiographs showing joint space narrowing, bone hyperplasia, subchondral osteosclerosis, and osteophyte formation.
* Patients who are between 45 and 85 years old.
* Patients who can understand and provide informed consent.
* Patients who are willing and able to undergo manual treatment for 1 course of treatment and cooperate with the doctor to complete the study.
Exclusion Criteria
* Severe knee pain with surgical indications (or X-ray grading standards reached level 4).
* Pregnant or planning to become pregnant.
* Patients who have participated in or are participating in other clinical trials within the last 3 months.
* Patients who have received or are receiving other treatment methods such as drugs that affect the evaluation of efficacy within the past 3 months.
* Patients with fractures, dislocation, skin damage, and severe infectious skin diseases within three weeks.
* Patients with severe primary diseases such as liver, kidney, hematopoietic system, endocrine system, cardiovascular and cerebrovascular, nervous system, tuberculosis, joint malformations, tumors, and psychiatric patients and postoperative patients.
* Patients who are unable to accurately evaluate the effectiveness and safety of treatment due to their medical condition.
45 Years
85 Years
ALL
No
Sponsors
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Xuhui Central Hospital, Shanghai
OTHER
Responsible Party
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Liang Qiao
Clinical Professor
Locations
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Qiao Liang
Shanghai, , China
Countries
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Other Identifiers
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XuhuiCH202405
Identifier Type: -
Identifier Source: org_study_id
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