Effect of Soleus Muscle Push Ups on Oxidative Stress and Inflammatory Markers, Soleus Endurance, and Adipocytokines Between Type 2 Diabetic, Overweight/Obese and Normal Weight Individuals.

NCT ID: NCT06450847

Last Updated: 2024-06-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

72 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-06-30

Study Completion Date

2024-10-31

Brief Summary

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The study aims to investigate the impact of Soleus Push Ups (SPU) on Soleus Muscle endurance, Oxidative Stress Markers, Inflammatory markers and Adipocytokines among people in the United Arab Emirates. This will be a pre-post intervention study with participants divided into three groups: Lean normal metabolic profile, metabolically healthy overweight/obese, and patients with Type 2 Diabetes Mellitus. Assessment of anthropometry and body composition, Soleus Muscle Endurance, blood tests for Inflammatory Markers, Oxidative Stress Markers, and Adipocytokines will be conducted pre and post-intervention.

Detailed Description

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Conditions

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Diabete Type 2 Obesity Overweight

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Interventional group

Group Type ACTIVE_COMPARATOR

Soleus Muscle Push Up Exercise

Intervention Type OTHER

Members will be asked to do the SPUs for 270 minutes/day for most days of the week (minimum 5 days) for 3 months:

1. Begin seated on a bench or chair so knees form a 90-degree angle with feet flat on the floor and toes pointed forward. Keep spine straight and shoulders back (not hunched or rounded forward).
2. Using a slow and controlled tempo, push toes into the floor and lift heels off the ground.
3. Hold for one to two seconds, pushing down on the balls of feet. Keep your thigh muscles relaxed.
4. Slowly lower heels and return to start. That's 1 rep. Without shoes Educational session will be given before the intervention time WhatsApp messages will be sent 1-2 times/day to remind the participants to continue doing the exercise and ascertain compliance. Also, the participants are required to daily fill logbook about the duration (in minutes) of the SPU that they did.

Control group

Group Type PLACEBO_COMPARATOR

Other Exercise

Intervention Type OTHER

Participants will be asked to continue their regular lifestyle

Interventions

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Soleus Muscle Push Up Exercise

Members will be asked to do the SPUs for 270 minutes/day for most days of the week (minimum 5 days) for 3 months:

1. Begin seated on a bench or chair so knees form a 90-degree angle with feet flat on the floor and toes pointed forward. Keep spine straight and shoulders back (not hunched or rounded forward).
2. Using a slow and controlled tempo, push toes into the floor and lift heels off the ground.
3. Hold for one to two seconds, pushing down on the balls of feet. Keep your thigh muscles relaxed.
4. Slowly lower heels and return to start. That's 1 rep. Without shoes Educational session will be given before the intervention time WhatsApp messages will be sent 1-2 times/day to remind the participants to continue doing the exercise and ascertain compliance. Also, the participants are required to daily fill logbook about the duration (in minutes) of the SPU that they did.

Intervention Type OTHER

Other Exercise

Participants will be asked to continue their regular lifestyle

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Residents of UAE, both males and females
* Ages 20-50 years
* Uncomplicated Type 2 Diabetic on meds,
* Normal lean BMI
* Overweight and Obese

Exclusion Criteria

* Recent orthopedic surgery in the LLs
* Pain in the LLs starting from Hips to Ankle.
* Presence of Varicose Veins in the LLs
* Present History of any cardiovascular condition
* Pregnant females
* Morbid Obesity
* Diabetics undergoing Insulin therapy only
* Smokers and alcohol consumption
Minimum Eligible Age

20 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Sharjah

OTHER

Sponsor Role lead

Responsible Party

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Amenah Hisham Abdelazim

Clinical Instructor

Responsibility Role PRINCIPAL_INVESTIGATOR

Central Contacts

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Amenah Abdelazim, BPT

Role: CONTACT

+971554590707

Kalyana Reddy, PhD

Role: CONTACT

+971503614889

Other Identifiers

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USharjah1

Identifier Type: -

Identifier Source: org_study_id

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