Pilot Study for the Early Detection of Chronic Kidney Disease, Non-Dialysis Objective (NDO).

NCT ID: NCT06447038

Last Updated: 2024-06-06

Basic Information

• Recruitment Status: ENROLLING_BY_INVITATION
• Total Enrollment: 10000 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2024-02-01
• Study Completion Date: 2024-12-31

Brief Summary

Chronic kidney disease (CKD) is a significant public health problem worldwide, affecting more than 10% of the Spanish population. Early detection is considered a top healthcare priority to establish strategies for preventing progression to more advanced stages of the disease and its complications. Additionally, CKD is associated with high comorbidity, poor prognosis, and substantial resource consumption within the healthcare system. In this context, albuminuria may be a more sensitive marker of CKD than reduced glomerular filtration rate (GFR), and it is also considered an indicator of not only renal damage but also "systemic damage" (generalized endothelial dysfunction, arterial remodeling, and increased cardiovascular risk) beyond the kidney. Furthermore, the reduction of proteinuria/albuminuria is clearly associated with a slower progression of CKD, making its reduction a therapeutic goal as well. Given this importance, this protocol aims to determine the urine albumin/creatinine ratio in all patients over 18 years old who visit their primary care physician in the province of Burgos, Spain, and require a blood test related to their reason for consultation.

Detailed Description

This is a protocol in which we seek to identify those patients with alterations incipient renal failure by determining the albumin/creatinine ratio in urine, test that is currently performed routinely in different groups of patients. By For this reason, the implementation of the non-dialysis objective protocol hopes to be implemented standardized form in patients who go to their primary attention doctor in the province of Burgos to later be extended to the entire Castilla y Leon community.

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Conditions

Chronic Kidney Disease (CKD)

Study Design

• Observational Model Type: ECOLOGIC_OR_COMMUNITY
• Study Time Perspective: PROSPECTIVE

Study Groups

Population

Population of the city of Burgos \> 18 years old.

albumin creatinine ratio

Intervention Type: DIAGNOSTIC_TEST

Albumin creatinine ratio, this test is routinely performed in urine.

Interventions

albumin creatinine ratio

Albumin creatinine ratio, this test is routinely performed in urine.

Intervention Type: DIAGNOSTIC_TEST

Eligibility Criteria

Inclusion Criteria

• Minimum age 18 years

Exclusion Criteria

• Age less than 18 years

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Hospital Universitario de Burgos

OTHER

Sponsor Role: lead

Responsible Party

Didier Sánchez OSpina

Doctor investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Maria J Izquierdo Ortiz, Doctor

Role: STUDY_DIRECTOR

HUBU

Emilio J Gonzalez Parra, Doctor

Role: PRINCIPAL_INVESTIGATOR

HUBU

Sebastian Mas Fontao, Doctor

Role: PRINCIPAL_INVESTIGATOR

HUBU

Maria Martin Palencia, Doctor

Role: PRINCIPAL_INVESTIGATOR

HUBU

Didier Sanchez, Doctor

Role: STUDY_DIRECTOR

HUBU

Locations

Maria J Izquierdo

Burgos, , Spain

Countries

Spain

References

Webster AC, Nagler EV, Morton RL, Masson P. Chronic Kidney Disease. Lancet. 2017 Mar 25;389(10075):1238-1252. doi: 10.1016/S0140-6736(16)32064-5. Epub 2016 Nov 23.

Reference Type: BACKGROUND

PMID: 27887750 (View on PubMed)

Other Identifiers

OND 01

Identifier Type: -

Identifier Source: org_study_id