FKBP5 Methylation and Childhood Emotional Abuse in Complex Posttraumatic Stress Disorder: Investigating the Relationship and Its Predictive Role in Therapy Outcome
NCT ID: NCT06433843
Last Updated: 2024-05-30
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
29 participants
INTERVENTIONAL
2016-01-31
2020-03-31
Brief Summary
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Detailed Description
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29 patients with cPTSD who participated in the DBT-PTSD program were enrolled. FKBP5 DNA methylation levels were measured at two CpG sites before treatment (n=25) and after completing DBT-PTSD (n=15). To assess the predictive value of FKBP5 DNA methylation, we categorized the sample into responders and non-responders based on therapy outcome.
Conditions
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Study Design
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NA
SINGLE_GROUP
TREATMENT
NONE
Study Groups
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cPTSD patients participating in 12-weeks DBT-PTSD program
The study consists of one arm including cPTSD patients, who participated in a 12-weeks dialectical behavioral therapy for the treatment of posttraumatic stress disorder (DBT-PTSD)
Dialectical behavioral therapy for the treatment of posttraumatic stress disorder (DBT-PTSD)
12 weeks inpatient disorder specific psychotherapy
Interventions
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Dialectical behavioral therapy for the treatment of posttraumatic stress disorder (DBT-PTSD)
12 weeks inpatient disorder specific psychotherapy
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
18 Years
65 Years
ALL
No
Sponsors
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University Hospital Tuebingen
OTHER
Responsible Party
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Locations
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University Hospital Tuebingen
Tübingen, Baden-Wurttemberg, Germany
Countries
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Other Identifiers
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090/2015BO2
Identifier Type: -
Identifier Source: org_study_id
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