Effect of Strontium-90 Brachytherapy Combined With Hyperthermia in the Treatment of Keloid

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-05-14

Study Completion Date

2025-06-30

Brief Summary

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Keloid patients were randomized into the experimental and control groups. Experimental group: Strontium-90 (Sr-90) brachytherapy followed by hyperthermia. Control group: Sr-90 brachytherapy alone .

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Detailed Description

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Sr-90 brachytherapy: 6-7 Gy each time, twice a week for 3 weeks; Hyperthermia: using a heater, 44℃ for 15 min

Conditions

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Keloid

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Experimental group

Sr-90 brachytherapy followed by hyperthermia.

Group Type EXPERIMENTAL

hyperthermia

Intervention Type OTHER

hyperthermia (using a heater, 44℃for 15 min)

Control group

Sr-90 brachytherapy alone.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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hyperthermia

hyperthermia (using a heater, 44℃for 15 min)

Intervention Type OTHER

Other Intervention Names

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heater

Eligibility Criteria

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Inclusion Criteria

* The patient was clinically diagnosed with keloid, and the keloid area was clean without rupture and exudation；
* Body surface keloid thickness: 2\~5mm, diameter ≥10mm.

Exclusion Criteria

* Women who plan to become pregnant within 3 months or are pregnant or breastfeeding;
* Patients with cicatricial constitution;
* Abnormal coagulation function;
* Patients who have received an adequate dose or course of radiation therapy;
* People with previous immune system diseases, diabetes and other metabolic diseases.

Minimum Eligible Age

16 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No