Comparative Study Between Intralesional Corticosteroid Injection Alone and Combined Intralesional Corticosteroid Injection With Either Long-pluse Nd YAG or Erbium Yag for Treating Hypertrophic or Keloid Scars

NCT ID: NCT07263100

Last Updated: 2025-12-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-05-01

Study Completion Date

2024-01-31

Brief Summary

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To compare the effectiveness of hypertrophic or keloid scar treatment with either intralesional corticosteroid injection alone or combined intralesional corticosteroid injection with either long-pulse ND YAG or Erbium YAG

Detailed Description

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Conditions

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Hypertrophic Scar Keloid Laser

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Keloidal scar

Randomly assigned keloid scar to each intervention (IL KA)

Group Type ACTIVE_COMPARATOR

Triamcinolone acetonide injection

Intervention Type DRUG

Long-pulse ND YAG and Erbium YAG laser device: Fotona Dynamis

Keloidal scar 2

Randomly assigned keloid scar to each intervention (IL KA + ND YAG)

Group Type EXPERIMENTAL

Fotona dynamis: Long pulse Nd YAG + Er YAG laser

Intervention Type DEVICE

Intralesional corticosteroid injection combine with long-pulse Neodynium-doped Yttrium Aluminium Garnet Laser (Nd-YAG) (IL KA + ND YAG)

Keloidal scar 3

Randomly assigned keloid scar to each intervention (ILKA + Er YAG)

Group Type EXPERIMENTAL

Fotona Dynamis: Long pulse Nd YAG + Er YAG laser

Intervention Type DEVICE

Intralesional corticosteroid injection combine with Erbium Yttrium Aluminium Garnet Laser (Er-YAG) (IL KA + Er YAG)

Interventions

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Triamcinolone acetonide injection

Long-pulse ND YAG and Erbium YAG laser device: Fotona Dynamis

Intervention Type DRUG

Fotona dynamis: Long pulse Nd YAG + Er YAG laser

Intralesional corticosteroid injection combine with long-pulse Neodynium-doped Yttrium Aluminium Garnet Laser (Nd-YAG) (IL KA + ND YAG)

Intervention Type DEVICE

Fotona Dynamis: Long pulse Nd YAG + Er YAG laser

Intralesional corticosteroid injection combine with Erbium Yttrium Aluminium Garnet Laser (Er-YAG) (IL KA + Er YAG)

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Individual with hypertrophic or keloid scars on any location
* Size of hypertrophic or keloid scars not larger than 20 cms in diameter

Exclusion Criteria

* Any topical or procedural treatment on scar in last 6 months
* Current corticosteroid use
* Bleeding disorders or coagulopathies
* Pregnancy or nursing
* Chronic kidney diseases
* Chronic liver diseases
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Somdech Phra Nangchao Sirikit Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Somdech Phra Nangchao Sirikit Hospital

Sattahip, Changwat Chon Buri, Thailand

Site Status

Countries

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Thailand

References

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Park JH, Jeong JW, Park JU. Efficacy of Nd:YAG Laser and Intralesional Triamcinolone Injection Combination Therapy in the Postoperative Management of Keloids. Aesthetic Plast Surg. 2025 Jan;49(2):576-583. doi: 10.1007/s00266-024-04433-z. Epub 2024 Oct 7.

Reference Type BACKGROUND
PMID: 39373734 (View on PubMed)

Other Identifiers

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RP009/66

Identifier Type: -

Identifier Source: org_study_id

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