Effect of Nd-YAG Laser on Hypertrophic Scar

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-05-01

Study Completion Date

2024-02-28

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

A hypertrophic scar is a serious health concern in the industrialized world. Two groups of patients were treated with standard medical care. The experimental group received additional laser therapy. scar assessment was measured immediately before treatment, after 3, and 7 months.

T test for comparison before-treatment between the control and study groups. ANOVA with repeated measures test for comparison among other measures.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Pulsed High Intensity Laser Versus Extracorporeal Shockwave Therapy on Hypertrophic Scar Post Burn

NCT06803472

Hypertrophic Scar

NOT_YET_RECRUITING NA

COMPARISON STUY OF KINESIOTAPE AND LOW-LEVEL LASER THERAPY ON HYPERTROPHIC SCAR

NCT07209891

Hypertrophic Scar Burn Scar (Post-burn) Burns

COMPLETED NA

Fractional Microneedling RF vs Intralesional Steroid With & Without Microneedling in Hypertrophic Scars

NCT04389619

Hypertrophic Scars

UNKNOWN NA

Comparison of Dual-mode ER:YAG Laser in Patients With Long Keloid/Hypertrophic Scars

NCT02546076

Keloid Hypertrophic Scars

WITHDRAWN PHASE2

Efficacy of Short Pulsed 1064 nm Nd-YAG Laser Versus 10600 nm Fractional CO2 Laser in Treatment of Striae Alba

NCT04092881

Striae Distensae Striae; Albicantes Striae Alba +6 more

UNKNOWN NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Background: A hypertrophic scar is a serious health concern in the industrialized world. Objective: The impact of this study was to investigate the effect of the Nd-YAG laser at 532nm wavelength on hypertrophic scars. Patients and methods: Forty male and female patients with hypertrophic scars, ranging in age from fifteen to forty-five, were recruited from the burn patients' clinic within the Faculty of Physical Therapy, Cairo University, for this study. They were randomized into two equivalent groups. Group A (the control group) consisted of 20 patients who were given standard medical care, nursing, physiotherapy, and a sham laser during the course of treatment. In contrast, Group B (the study group) consisted of 20 patients who were given 532 nm laser radiation in addition to standard medical care, nursing, and physiotherapy. Treatment was conducted every 2 weeks for 14 sessions. Outcome measures included Vancouver Scar Scale score and scar volume. The assessment procedures were applied before the initiation of treatment (Pre), after 3 months (Post1) and after 7 months (Post 2) from the beginning of the treatment.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Hypertrophic Scar

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

one treatment one control group

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Placebo

Patients received standard medical care, nursing, physiotherapy, and a sham laser during the course of treatment

Group Type PLACEBO_COMPARATOR

Nd- YAG laser at 532nm wavelength

Intervention Type PROCEDURE

Nd-YAG laser at 532nm wavelength every 2 weeks for 14 sessions. patients will also receive standard medical care, nursing, physiotherapy

Laser group

Patients received 532 nm laser radiation in addition to standard medical care, nursing, and physiotherapy.

Group Type ACTIVE_COMPARATOR

Nd- YAG laser at 532nm wavelength

Intervention Type PROCEDURE

Nd-YAG laser at 532nm wavelength every 2 weeks for 14 sessions. patients will also receive standard medical care, nursing, physiotherapy

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Nd- YAG laser at 532nm wavelength

Nd-YAG laser at 532nm wavelength every 2 weeks for 14 sessions. patients will also receive standard medical care, nursing, physiotherapy

Intervention Type PROCEDURE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

• Adult patients with hypertrophic scars.

Exclusion Criteria

* Patients were excluded if they had taken oral retinoids in the last year.
* Patients had any skin defects.
* Patients had any history of photosensitivity.
* Patients experienced active skin diseases in the treatment regions (such as psoriasis, cancer, or autoimmune disease).

Minimum Eligible Age

30 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No