MIND Diet and Cognitive Function in Middle-aged and Older Adults

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

1200 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-05-10

Study Completion Date

2025-10-10

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

A 12-month cluster-randomized controlled trial designed to test the effect of the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet education on the rate of cognitive change and several other secondary outcomes in 1200 adults aged 40-69 years.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

MIND Diet and Cognitive Function in Adults With MCI

NCT05975723

Mild Cognitive Impairment Cognitive Function Cognitive Decline

UNKNOWN NA

MINDSpeed Food and Brain Training RCT

NCT03419052

Low Education Cognition Cognitive Training +1 more

COMPLETED NA

Remote Evaluation of MIND Diet

NCT06450977

Multiple Sclerosis Cognitive Change Nutrition, Healthy

RECRUITING NA

Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Diet in Stroke Patients Patients

NCT04337255

Cognitive Decline Dementia, Vascular Alzheimer Disease +2 more

ACTIVE_NOT_RECRUITING NA

Motor-cognitive Interventions Are Effective in Improving Cognitive Function in Older Adults With Mild Cognitive impairment--a Chinese Sample

NCT05764421

MCI

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Diet and Cognitive Decline in Middle-aged and Elderly People is a 12-month cluster-randomized controlled trial designed to test the effect of the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet education on the rate of cognitive change and several other secondary outcomes in 1200 adults aged 40-69 years. The proposed MIND diet for this study is a hybrid of the Mediterranean and DASH diets but with selected modifications based on the most compelling evidence in the diet-dementia field and Chinese Dietary Guidelines 2022. Specifically, the proposed MIND diet education will emphasize the consumption of whole grains, dark green leafy vegetables, dark red/yellow vegetables, other vegetables, berries and citrus, poultry, fish and seafood, beans and legumes, nuts, olive and seed oils, and green tea, and restrict red and processed meats, animal fat, fried foods, and sweets and pastries. The trial will employ a cluster randomization design comparing the effects on cognitive change of the MIND intervention diet education among 1200 adults aged 40-69 years. Secondary outcomes will include dietary behavior changes, health status changes, etc. The proposed study is sited at Taian, Shandong, China.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Cognitive Function Dementia

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

This is a two-arm parallel design, with one arm being the control arm and the other being the intervention arm (MIND diet education and food supply).

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Outcome Assessors

This is a single-blind design, where the outcome assessors will be masked from the assignment of the participants.

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Control arm

General dietary advice

Group Type PLACEBO_COMPARATOR

Control arm

Intervention Type BEHAVIORAL

Participants will receive a copy of the Chinese Dietary Guidelines leaflet at baseline.

Intervention arm

MIND diet education

Group Type ACTIVE_COMPARATOR

Intervention arm

Intervention Type BEHAVIORAL

Participants will be given three MIND diet education videos on different topics at baseline and during follow-up. In addition, each participant will receive a MIND diet education brochure at baseline and some food supply during follow-up.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Control arm

Participants will receive a copy of the Chinese Dietary Guidelines leaflet at baseline.

Intervention Type BEHAVIORAL

Intervention arm

Participants will be given three MIND diet education videos on different topics at baseline and during follow-up. In addition, each participant will receive a MIND diet education brochure at baseline and some food supply during follow-up.

Intervention Type BEHAVIORAL

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Normal chewing function, able to eat hard foods such as nuts.
* Willing to participate and sign an informed consent form.
* Able to understand research procedures and adhere to them throughout the entire study period.

Exclusion Criteria

* Participation in or have participated in other clinical trial studies within the past year.
* Medication to treat Alzheimer's or Parkinson's disease.
* Diagnosis of severe chronic diseases, such as cancer.

Minimum Eligible Age

40 Years

Maximum Eligible Age

69 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes