Decreasing Nightmares in Adults With Narcolepsy

NCT ID: NCT06383806

Last Updated: 2025-07-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-06-06

Study Completion Date

2027-09-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this clinical trial is learn whether a behavioral (non-medication) treatment can reduce nightmares in adults with narcolepsy. All participants will receive the treatment and will complete three assessments. Half of the participants will receive the treatment after the first assessment, and half will receive it after the second assessment. Romantic partners of participants with narcolepsy will also be eligible to enroll in the study. Partners will complete three assessments but will not participate in the treatment.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Narcolepsy Narcolepsy Type 1 Narcolepsy With Cataplexy Narcolepsy Without Cataplexy Nightmare Nightmare Disorder With Associated Other Sleep Disorder

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Waitlist control
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Treatment

The Treatment arm will receive the intervention immediately following the first assessment.

Group Type EXPERIMENTAL

Imagery Rehearsal Therapy (IRT)

Intervention Type BEHAVIORAL

The intervention will consist of 7 therapy sessions (once per week for 7 weeks) which will be delivered via videoconference. During the sessions, participants will learn techniques for managing and changing nightmares.

Waitlist

The Waitlist arm will undergo a waiting period following the first assessment and then will receive the treatment after the second assessment.

Group Type OTHER

Imagery Rehearsal Therapy (IRT)

Intervention Type BEHAVIORAL

The intervention will consist of 7 therapy sessions (once per week for 7 weeks) which will be delivered via videoconference. During the sessions, participants will learn techniques for managing and changing nightmares.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Imagery Rehearsal Therapy (IRT)

The intervention will consist of 7 therapy sessions (once per week for 7 weeks) which will be delivered via videoconference. During the sessions, participants will learn techniques for managing and changing nightmares.

Intervention Type BEHAVIORAL

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

Cognitive Behavioral Therapy for Nightmares (CBT-N)

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Diagnosis of narcolepsy type 1 or narcolepsy type 2
* Nightmare frequency of ≥1 times per week
* Age 18 or older
* Able to speak, read, and write in English
* Live in the United States
* Sleep and psychiatric medications stable for ≥ 1 month and willing to keep medications stable for the duration of the study


* Live with a romantic partner who meets the above criteria and has agreed to participate in the study
* Age 18 or older
* Able to speak, read, and write in English
* Live in the United States

Exclusion Criteria

* Currently engaged in trauma- or sleep-related psychotherapy
* Previous behavioral treatment for nightmares
* Medical, psychiatric, or cognitive condition which would interfere with ability to engage in the treatment
* Untreated moderate-severe sleep apnea

PARTICIPANTS WHO ARE PARTNERS OF SOMEONE WITH NARCOLEPSY
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

University of Utah

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Jennifer Mundt

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

University of Utah

Salt Lake City, Utah, United States

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

United States

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Jennifer Mundt, PhD

Role: CONTACT

801-646-8287

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Jennifer Mundt, PhD

Role: primary

801-646-8287

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

372-SR-25

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

IRB_00188162

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Chronic Sleep Restriction
NCT01493661 COMPLETED
Pilot Study on Sleep Management for US Veterans
NCT00933959 COMPLETED PHASE1/PHASE2