Improving Social Relationships for Adolescents with Central Disorders of Hypersomnolence

NCT ID: NCT06251063

Last Updated: 2025-02-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

45 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-04-01

Study Completion Date

2025-05-01

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The goal of this study is to test a web-based psychoeducational resource for adolescents with central disorders of hypersomnolence and their families. The investigators hope to assess the website's usability, acceptability, and feasibility, as well as its potential effect on social relationship health.

Participants will be asked to review the content of the psychoeducational websites. The participants will then provide feedback on the website, as well as the adolescent's social relationships and social health before and after reviewing the website through online surveys.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The American Academy of Sleep Medicine's clinical practice guideline task force concluded that "reliance on medications alone to treat CNS hypersomnia conditions is likely insufficient." Our stakeholder data demonstrated that this issue is a significant challenge in the domain of social relationship health for children with narcolepsy type 1 and 2 (NT1/NT2) and idiopathic hypersomnia (IH). With one peak for symptom onset in adolescence, a critical period in a child's social development, children with NT1/NT2/IH and their families report significant social sequelae of the disorder and its treatment that have lifelong implications. To address this important, yet consistently overlooked real-life concern for adolescents with CDH, the investigators intend to assess an online psychoeducational website that the investigators designed to provide families with the knowledge and resources to improve the adolescent's social relationship health.

A total of 45 families will participate in a single-arm usability, feasibility, and acceptability trial. Eligible families will be provided with instructions on how to access the website. Participants will be encouraged to return to the website as often as needed to review content. For the purposes of this study, participants will be instructed to review all intervention materials within one month of receiving website access. The participants will then complete feedback questionnaires on the secure online platform REDCap. This study will inform a future randomized controlled trial testing the efficacy of the investigators' intervention. The investigators' stakeholder informed program will be the first of its kind for children with NT1/NT2/IH, with the potential to be widely disseminated.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Narcolepsy Type 1 Narcolepsy Type 2 Idiopathic Hypersomnia

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Web-based psychoeducational Resource

Eligible families will be provided with website access instructions. Parents and children will be instructed to review the materials separately. The intervention will provide each person with individualized action items to be discussed as a family. It is anticipated that reviewing all of the psychoeducational materials will take the parent/child approximately one hour, resulting in a total intervention burden of two hours for the family. Participants will be encouraged to return to the website as often as needed to review content. For the purposes of this project, they will be instructed to review all intervention materials within one month of receiving the website access instructions.

Group Type EXPERIMENTAL

Web-based psychoeducational resource

Intervention Type BEHAVIORAL

The website will incorporate animations/illustrations to enhance comprehension, patient stories, and video-based expert explanations.

The materials will address the following content areas:

* Provide families with data demonstrating how prevalent social relationship struggles are for children with CDH.
* Describe specific social challenges that commonly affect children with CDH.
* Explain the impact that medications typically prescribed for CDH may have on social relationship health.
* Help families advocate for their child's social needs at school.
* Support children and their families in decision-making about appropriate disclosure with peers at school and in extracurricular settings.
* Offer strategies to support families in raising the issue of social relationship health with the child's sleep physician.
* Provide a list of programming which offers children both structured and unstructured opportunities for social engagement

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Web-based psychoeducational resource

The website will incorporate animations/illustrations to enhance comprehension, patient stories, and video-based expert explanations.

The materials will address the following content areas:

* Provide families with data demonstrating how prevalent social relationship struggles are for children with CDH.
* Describe specific social challenges that commonly affect children with CDH.
* Explain the impact that medications typically prescribed for CDH may have on social relationship health.
* Help families advocate for their child's social needs at school.
* Support children and their families in decision-making about appropriate disclosure with peers at school and in extracurricular settings.
* Offer strategies to support families in raising the issue of social relationship health with the child's sleep physician.
* Provide a list of programming which offers children both structured and unstructured opportunities for social engagement

Intervention Type BEHAVIORAL

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Adolescent from 10-17 years of age and parent of the adolescent
* Adolescent has physician-diagnosed narcolepsy type 1 or type 2, or idiopathic hypersomnia
* English fluency
* Interest in learning more about how to improve social health for adolescents with a CDH
Minimum Eligible Age

10 Years

Maximum Eligible Age

17 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

American Academy of Sleep Medicine

OTHER

Sponsor Role collaborator

Boston Children's Hospital

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Eric Zhou, PhD

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Eric Zhou, PhD

Role: PRINCIPAL_INVESTIGATOR

Boston Children's Hospital

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Boston Children's Hospital

Boston, Massachusetts, United States

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

United States

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Grace Y Wang

Role: CONTACT

617-919-6212

Eric Zhou, PhD

Role: CONTACT

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Eric Zhou, PhD

Role: primary

References

Explore related publications, articles, or registry entries linked to this study.

Zhou ES, Revette A, Heckler GK, Worhach J, Maski K, Owens JA. Building a deeper understanding of social relationship health in adolescents with narcolepsy disorder. J Clin Sleep Med. 2023 Mar 1;19(3):491-498. doi: 10.5664/jcsm.10372.

Reference Type BACKGROUND
PMID: 36468655 (View on PubMed)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

IRB-P00047080

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Narcolepsy Nightmare Study
NCT05709873 COMPLETED NA
Chronic Sleep Restriction
NCT01493661 COMPLETED
Teen Sleep Health Study
NCT04087603 COMPLETED NA
Sleep Promotion Program Primary Care
NCT06240325 RECRUITING NA