Sleep Duration Required to Restore Performance During Chronic Sleep Restriction

NCT ID: NCT01581125

Last Updated: 2016-07-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

19 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-04-30

Study Completion Date

2016-06-30

Brief Summary

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The purpose of this study is to test the hypothesis that sleep and performance depend on length of time awake, length of time asleep, the amount of sleep over several sleep episodes, and circadian phase.

Detailed Description

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The purpose of this study is to test the hypothesis that sleep and performance depend on length of time awake, length of time asleep, the amount of sleep over several sleep episodes, and circadian phase. Inpatient sleep and performance data will be collected from healthy volunteers.

Conditions

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Sleep Sleep Deprivation Insufficient Sleep Syndrome

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

SINGLE

Participants

Study Groups

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Sleep:wake 2

Sleep and wake durations for arm 2 for inpatient portion of protocol. .There are a variety of sleep and wake durations during the protocol; some of these are longer and some are shorter and some are the same as in arm 1.

Group Type EXPERIMENTAL

Sleep:wake 2

Intervention Type BEHAVIORAL

Sleep and Wake durations for arm2

Sleep:wake 1

Sleep and wake durations for arm 1 of the inpatient portion of the protocol. There are a variety of sleep and wake durations during the protocol; some of these are longer and some are shorter and some are the same as in arm 2.

Group Type EXPERIMENTAL

Sleep:wake 1

Intervention Type BEHAVIORAL

Sleep and Wake durations for arm 1

Interventions

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Sleep:wake 1

Sleep and Wake durations for arm 1

Intervention Type BEHAVIORAL

Sleep:wake 2

Sleep and Wake durations for arm2

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Healthy

Exclusion Criteria

* Prescription medications
Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Brigham and Women's Hospital

OTHER

Sponsor Role lead

Responsible Party

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Elizabeth B. Klerman

Associate Professor, Associate Physician

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Elizabeth B Klerman, MD PhD

Role: PRINCIPAL_INVESTIGATOR

Brigham and Women's Hospital

Locations

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Brigham and Women's Hospital

Boston, Massachusetts, United States

Site Status

Countries

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United States

References

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McHill AW, Hull JT, Cohen DA, Wang W, Czeisler CA, Klerman EB. Chronic sleep restriction greatly magnifies performance decrements immediately after awakening. Sleep. 2019 May 1;42(5):zsz032. doi: 10.1093/sleep/zsz032.

Reference Type DERIVED
PMID: 30722039 (View on PubMed)

McHill AW, Hull JT, McMullan CJ, Klerman EB. Chronic Insufficient Sleep Has a Limited Impact on Circadian Rhythmicity of Subjective Hunger and Awakening Fasted Metabolic Hormones. Front Endocrinol (Lausanne). 2018 Jun 12;9:319. doi: 10.3389/fendo.2018.00319. eCollection 2018.

Reference Type DERIVED
PMID: 29946297 (View on PubMed)

Other Identifiers

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NIH R01 HL114088-01

Identifier Type: -

Identifier Source: org_study_id

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