A Naturalistic Study Investigating Sleep and Cognitive Learning in Children With and Without Tic Disorders
NCT ID: NCT02676492
Last Updated: 2017-08-22
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
32 participants
OBSERVATIONAL
2016-03-31
2017-03-31
Brief Summary
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Detailed Description
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TS/CTD are movement disorders characterized by repetitive involuntary movements and/or vocalizations called tics. Sleep related problems are commonly reported for children with TS/CTD and may include problems getting to sleep, waking up frequently during the night, early wakening and tic-related movements in sleep. For typically developing children, sleep disturbances have been linked to problems with mood, behaviour and learning. To date, the relationship between sleep and learning has not been explored for children with TS/CTD.
The aim of this project is to investigate whether there is a relationship between sleep efficiency and learning in boys with and without TS/CTD aged 11-14 years.
Sleep efficiency will be measured using a small actigraphy watch, which will collect information about movements during sleep, night time waking and light exposure. Children will be required to wear the watch for 14 days and nights. Before one night of sleep and again the next morning, children will be asked to complete some tasks on an iPad Air to assess learning. These include 1) 'popping' balloons with faces on them according to specific rules (e.g. boys faces, happy faces), 2) learning novel animal names, 3) navigating a 3D maze. Children will also be administered some standard tests to look at level of intellectual functioning, memory and other thinking skills that may contribute to performance on the computerized tasks. Additionally, children and their parents will be asked to complete questionnaires to assess tics, quality of life, mood and behaviour. The findings of this study will help improve understanding of sleep problems for children with tic disorders to aid the development of specific interventions for this group.
Conditions
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Study Design
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CASE_CONTROL
CROSS_SECTIONAL
Study Groups
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Tic Disorder
Boys with a diagnosis of Tourette Syndrome (TS) or chronic tic disorder (CTD) aged 11-14 years
Actigraphy to measure sleep duration and efficiency
Actigraphy watch to be worn on participants' wrist for 14 days and nights
'Sleepsuite' novel cognitive learning tasks
Novel iPad-administered learning tasks, to be completed one evening and the next morning during actigraphy monitoring period.
Control
Boys aged 11-14 years without a diagnosis of TS/CTD (i.e. typically developing)
Actigraphy to measure sleep duration and efficiency
Actigraphy watch to be worn on participants' wrist for 14 days and nights
'Sleepsuite' novel cognitive learning tasks
Novel iPad-administered learning tasks, to be completed one evening and the next morning during actigraphy monitoring period.
Interventions
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Actigraphy to measure sleep duration and efficiency
Actigraphy watch to be worn on participants' wrist for 14 days and nights
'Sleepsuite' novel cognitive learning tasks
Novel iPad-administered learning tasks, to be completed one evening and the next morning during actigraphy monitoring period.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Currently taking medications to support tic, mood and/or behaviour management
11 Years
14 Years
MALE
Yes
Sponsors
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Guy's and St Thomas' NHS Foundation Trust
OTHER
King's College London
OTHER
Responsible Party
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Principal Investigators
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Sally Robinson
Role: PRINCIPAL_INVESTIGATOR
Guy's and St Thomas' NHS Foundation Trust
Locations
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Evelina Children's Hospital, St Thomas' Hospital
London, , United Kingdom
Countries
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Other Identifiers
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HR-15/16-2278
Identifier Type: -
Identifier Source: org_study_id
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