Ningbo Schizophrenia Cohort

NCT ID: NCT06370793

Last Updated: 2025-05-23

Basic Information

• Recruitment Status: ACTIVE_NOT_RECRUITING
• Total Enrollment: 26899 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2018-07-01
• Study Completion Date: 2026-12-31

Brief Summary

In recent years, the prevalence of schizophrenia in China has continued to grow, and the burden of disease in society has continued to rise. In order to improve the prognosis of patients with schizophrenia and reduce the risk of disease relapse or readmission, researchers established a cohort based on the Ningbo Mental Health Information System in Ningbo, a sub-provincial city in the southern wing of the Yangtze River Delta of China, with a resident population of more than 9 million, and linked it to the residents' health records, and through the data linkage obtained data on patients in the full cycle of pre-onset, diagnosis, follow-up, disease changes and death, realising full-cycle management of patients with schizophrenia.

Currently, NSC has accumulated data on more than 30,000 patients with schizophrenia and obtained multi-dimensional longitudinal information through long-term follow-up and data linkage. All diseases follow the World Health Organization International Classification of Diseases 10th Edition (ICD-10) for clinical coding, and available data include baseline demographics, past history, family history, social functioning deficit screening scale scores, risk assessment, and so on and longitudinal health information from electronic health records (EHR), providing a solid data base for future real-world studies.

Conditions

Schizophrenia

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

Patients with Schizophrenia

Patient with schizophrenia without intervention

Intervention Type: OTHER

Patients with schizophrenia identified based on exposures of interest to the study

Interventions

Patient with schizophrenia without intervention

Patients with schizophrenia identified based on exposures of interest to the study

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Clinical diagnosis of schizophrenia (F20)
• Aged 18-65 years at the time of diagnosis

Exclusion Criteria

• None.

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 65 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

The Affiliated Kangning Hospital of Ningbo University

UNKNOWN

Sponsor Role: collaborator

Ningbo University

OTHER

Sponsor Role: lead

Responsible Party

Liya Liu

Associate Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Ningbo University

Ningbo, Zhejiang, China

Countries

China

References

Ye H, Zhao Y, Li L, Qian Y, Zhu H, Bian G, Liu L. Ningbo Schizophrenia Cohort (NSC)-a longitudinal ambispective cohort based on electronic health records: cohort profile. BMJ Open. 2025 May 15;15(5):e091188. doi: 10.1136/bmjopen-2024-091188.

Reference Type: DERIVED

PMID: 40379328 (View on PubMed)

Other Identifiers

NBU-2024-011

Identifier Type: -

Identifier Source: org_study_id