Psychiatric Multi-omics and Neuroimaging Project

NCT ID: NCT06580860

Last Updated: 2024-09-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Total Enrollment

1899 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-01-31

Study Completion Date

2025-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This study focuses on the structure and function of the brain and gene expression in peripheral blood of patients with schizophrenia, to explore the interaction and influence between the three. Patients with mental disorders who have been recruited will take their medication regularly for 1 year and participate in baseline and follow-up assessments.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The study seeks to identify possible biological markers of schizophrenia and the effects of gene-environment interactions on brain structural and functional networks. So we can help doctors and scientific researchers better understand the neuropathological basis of schizophrenia.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Mental Disorders Healthy Control

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

PMNP-Healthy Norms

Healthy Norms

Antipsychotic drugs, antidepressants, mood stabilizers, and sleep aids

Intervention Type DRUG

Patients with mental disorders should take the appropriate medicine as prescribed by the doctor,and the health norms are not required to take medicine.This study will not interfere with the medication regimen of doctors.

PMNP-Subclinical high-risk

Subclinical high-risk

Antipsychotic drugs, antidepressants, mood stabilizers, and sleep aids

Intervention Type DRUG

Patients with mental disorders should take the appropriate medicine as prescribed by the doctor,and the health norms are not required to take medicine.This study will not interfere with the medication regimen of doctors.

PMNP-Schizophrenia and Psychosis

Schizophrenia and Psychosis patient

Antipsychotic drugs, antidepressants, mood stabilizers, and sleep aids

Intervention Type DRUG

Patients with mental disorders should take the appropriate medicine as prescribed by the doctor,and the health norms are not required to take medicine.This study will not interfere with the medication regimen of doctors.

PMNP-MDD

major depressive disorder patient

Antipsychotic drugs, antidepressants, mood stabilizers, and sleep aids

Intervention Type DRUG

Patients with mental disorders should take the appropriate medicine as prescribed by the doctor,and the health norms are not required to take medicine.This study will not interfere with the medication regimen of doctors.

PMNP-ASD

autism spectrum disorder patient

Antipsychotic drugs, antidepressants, mood stabilizers, and sleep aids

Intervention Type DRUG

Patients with mental disorders should take the appropriate medicine as prescribed by the doctor,and the health norms are not required to take medicine.This study will not interfere with the medication regimen of doctors.

PMNP-BD

bipolar disorder patient

Antipsychotic drugs, antidepressants, mood stabilizers, and sleep aids

Intervention Type DRUG

Patients with mental disorders should take the appropriate medicine as prescribed by the doctor,and the health norms are not required to take medicine.This study will not interfere with the medication regimen of doctors.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Antipsychotic drugs, antidepressants, mood stabilizers, and sleep aids

Patients with mental disorders should take the appropriate medicine as prescribed by the doctor,and the health norms are not required to take medicine.This study will not interfere with the medication regimen of doctors.

Intervention Type DRUG

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Age: 13-35 years old(Patients with healthy siblings can be extended to 14-35 years of age)
* Course of disease: \<24 months
* Priority is given to patients who have never taken medicine or duration of drug use \< 2 weeks
* No nuclear magnetic contraindications.

Exclusion Criteria

* Family history of psychotic disorders, history of psychoactive substances abuse, alcohol dependence, or nicotine dependence
* Have a major physical disease or infectious disease
* History of coma and serious neurological disease 4.MRI contraindications.
Minimum Eligible Age

13 Years

Maximum Eligible Age

35 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

mingjun Zhong

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

mingjun Zhong

Principal Investigator

Responsibility Role SPONSOR_INVESTIGATOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

The Second Xiangya hospital of central south univerity

Changsha, Hunan, China

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

China

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Yunzhi Pan

Role: CONTACT

15074818197

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Yunzhi Pan

Role: primary

15074818197

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

NSFC82201664

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.