Book Sharing for Toddlers With Clefts

NCT ID: NCT06338319

Last Updated: 2025-05-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ENROLLING_BY_INVITATION

Clinical Phase

NA

Total Enrollment

320 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-05-01

Study Completion Date

2028-08-31

Brief Summary

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Children with clefts exhibit difficulty with language and literacy compared to children without clefts. However, little is known about interventions to address these difficulties in the cleft population. This study will test the efficacy of a parent-focused dialogic book-sharing intervention for toddlers with isolated cleft palate. The study will use a randomized controlled trial (RCT) design and Intention to Treat (ITT) analyses. Child outcomes include expressive and receptive language. Parent outcomes of interest include the frequency and quality of shared reading interactions. To assess mechanisms of action, the study will test whether changes in child outcomes are mediated by changes in parents' behavior. Analyses will also explore heterogeneity in outcomes to determine whether the intervention is more effective in certain clinical or demographic sub-groups.

Detailed Description

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Conditions

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Cleft Palate Cleft Lip and Palate

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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BOOST Program

Parents in the BOOST Program group will receive books to read with their children and send smartphone video recordings of their reading interactions.

To provide support, parents will participate in 3 remote, parent-focused book-sharing intervention sessions

Group Type EXPERIMENTAL

Book-Sharing for Toddlers with Clefts (BOOST)

Intervention Type BEHAVIORAL

BOOST is a dialogic book-sharing intervention. Topics covered include strategies to increase the frequency of shared reading, child engagement and involvement in reading, and strategies to promote language development. Handouts will be shared during the sessions (using the Zoom share screen feature) and sent to families to summarize the content. Parents will record and securely upload shared reading videos during the intervention period. The research team will send prompts for these video uploads after each intervention session. Interventionists will review these videos between sessions to identify parent strengths, application of target skills, and opportunities for improvement.

Standard of Care Comparison Group

Parents in the Standard of Care Comparison Group will receive books to read with their children and send smartphone video recordings of their reading interactions.

Parents in the comparison group will not participate in BOOST intervention sessions.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Book-Sharing for Toddlers with Clefts (BOOST)

BOOST is a dialogic book-sharing intervention. Topics covered include strategies to increase the frequency of shared reading, child engagement and involvement in reading, and strategies to promote language development. Handouts will be shared during the sessions (using the Zoom share screen feature) and sent to families to summarize the content. Parents will record and securely upload shared reading videos during the intervention period. The research team will send prompts for these video uploads after each intervention session. Interventionists will review these videos between sessions to identify parent strengths, application of target skills, and opportunities for improvement.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* A child's parent or primary caregiver provides a signed and dated informed consent form and permission for their child to participate.
* A child's parent is willing to comply with all study procedures and be available for the duration of the study.
* Child is between the ages of 20 to 32 months at the time of enrollment.
* Child has been diagnosed with isolated cleft palate, with or without cleft lip.
* Child has received palate repair surgery.
* The family's preferred language is English or Spanish.
* The family has access to a smartphone or similar device (e.g., tablets) capable of recording and sending videos.

Exclusion Criteria

* Diagnosed genetic condition associated with developmental delay (e.g., 22q11 deletion).
* The child has a diagnosis of autism spectrum disorder
* The child has a tracheostomy tube
* Child delivered \< 32 weeks' gestation.
* Child in state custody or foster care.
* Child with significant sensory impairment (blindness, sensorineural hearing loss).
* The caregiver speaks a language other than English or Spanish
* The caregiver does not own a smartphone or similar device capable of recording/sending video
Minimum Eligible Age

20 Months

Maximum Eligible Age

32 Months

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Washington

OTHER

Sponsor Role collaborator

Nationwide Children's Hospital

OTHER

Sponsor Role collaborator

Children's Hospital Los Angeles

OTHER

Sponsor Role collaborator

Ohio State University

OTHER

Sponsor Role collaborator

Seattle Children's Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Brent Collett, PhD

Role: PRINCIPAL_INVESTIGATOR

Seattle Children's Hospital

Locations

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Seattle Children's Hospital

Seattle, Washington, United States

Site Status

Countries

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United States

Other Identifiers

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23-048-E

Identifier Type: -

Identifier Source: org_study_id

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