Effects of Recursive Self-feedback on Speech Production in Aphasia

NCT ID: NCT06323629

Last Updated: 2024-03-21

Basic Information

• Recruitment Status: NOT_YET_RECRUITING
• Clinical Phase: NA
• Total Enrollment: 45 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2024-04-30
• Study Completion Date: 2025-03-31

Brief Summary

The goal of this clinical trial is to test the effects of recursive self-feedback procedures on spontaneous speech production in stroke survivors with impaired speech production (aphasia). The main question it aims to answer is:

• To what extent can stroke survivors with aphasia use their self-feedback alone to improve their spontaneous speech production?

Participants will be engaged in the following activities:

• They will perform language and cognitive tasks.
• Afterwards, they will receive treatments using tablets and headphones at no cost to them.
• The experimental treatments (recursive self-feedback procedures) entails responding to prompts, listening to playbacks of their speech response and attempt to minimize/correct the errors in the next attempt. This process will be repeated multiple times per prompt.
• The experimental treatments are two: an adaptive version that adapts the complexity of the treatment prompt and a non-adaptive version that does not adapt task complexity.
• Researchers will compare the experimental treatments to see if both have similar effects on improving spontaneous speech production.

Conditions

Aphasia; Stroke

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: SINGLE

Study Groups

Adaptive recursive self-feedback procedure

Using a tablet, participants listen to speech playback of their response to a prompt and self-correct/minimize their speech errors in a subsequent attempt. This process is looped multiple times per prompt. It adapts across narrative prompts with low and high complexities.

Group Type: EXPERIMENTAL

Adaptive recursive self-feedback procedure

Intervention Type: BEHAVIORAL

The intervention uses self-feedback alone to improve speech production. It adapts the complexity of the treatment tasks.

Non-adaptive recursive self-feedback procedure

Using a tablet, participants listen to speech playback of their response to a prompt and self-correct/minimize their speech errors in a subsequent attempt. This process is looped multiple times per prompt. However, it only uses narrative prompts with high complexity.

Group Type: EXPERIMENTAL

Non-adaptive recursive self-feedback procedure

Intervention Type: BEHAVIORAL

The intervention uses self-feedback alone to improve speech production. However, it does not adapt the complexity of the treatment tasks.

Interventions

Adaptive recursive self-feedback procedure

The intervention uses self-feedback alone to improve speech production. It adapts the complexity of the treatment tasks.

Intervention Type: BEHAVIORAL

Non-adaptive recursive self-feedback procedure

The intervention uses self-feedback alone to improve speech production. However, it does not adapt the complexity of the treatment tasks.

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• 6 months post left hemisphere stroke
• Aphasia due to left hemisphere stroke
• Dominant English speaker

Exclusion Criteria

• Speech-language deficits due to neurological insults such as Parkinson's disease, neurodegenerative conditions etc.
• Uncorrected sensory impairments.
• Language comprehension impairment.
• Severe cognitive impairment.

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 80 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Center for Smart Use of Technologies to Assess Real-world Outcomes

UNKNOWN

Sponsor Role: collaborator

University of South Florida

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Gerald C. Imaezue, PhD

Role: PRINCIPAL_INVESTIGATOR

University of South Florida

Central Contacts

Gerald C. Imaezue, PhD

Role: CONTACT

gimaezue@usf.com

(813)974-2464

William Burgin, MD

Role: CONTACT

wburgin@usf.edu

813-259-8577

Other Identifiers

STUDY006201

Identifier Type: -

Identifier Source: org_study_id