Phonomotor Treatment of Word Retrieval Deficits in Individuals With Aphasia

NCT ID: NCT01163461

Last Updated: 2017-08-31

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 28 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2010-09-01
• Study Completion Date: 2014-09-30

Brief Summary

This is a behavioral speech therapy trial for individuals who have suffered a stroke on the left side of the brain and have difficulty speaking. The name of this disorder is called 'aphasia'. Individuals who participate in this study will receive 60 hours of therapy for free (2 hours/day, 5 days/week, 6 weeks).

Detailed Description

The study design was a single group (n=26) with repeated testing (3 times) pre- and post-treatment. All participants received the same treatment protocol (described in detail in Appendix A and in Minkina et al. (under review)). In order to control for improvement in language function related to passage of time, and for the effect of repeated exposure to outcome measures, individuals were randomly assigned to one of two conditions: delayed treatment or immediate treatment (Figure 2). Participants who were randomized to the delayed group received repeated testing three times before and three times after a six-week delay. During the delay phase they were permitted to participate in usual speech-language care (e.g., conversation groups and individual therapy).

Standardized assessments and outcome measures (described in detail below) were administered prior to the start of treatment (for both immediate and delayed groups), at the end of the delay phase (delayed group only), immediately after treatment termination, and at three months post-treatment.

Conditions

Aphasia

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: TREATMENT
• Blinding Strategy: SINGLE

Study Groups

Immediate Treatment

individuals will receive 60 hours of speech therapy

Group Type: EXPERIMENTAL

speech therapy

Intervention Type: BEHAVIORAL

individuals will receive 60 hours of behavioral speech therapy

Delayed Treatment

individuals will receive 60 hours of speech therapy after 6 week delay period

Group Type: EXPERIMENTAL

speech therapy

Intervention Type: BEHAVIORAL

individuals will receive 60 hours of behavioral speech therapy

Interventions

speech therapy

individuals will receive 60 hours of behavioral speech therapy

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• left hemisphere stroke
• monolingual English speaking
• right handed
• presence of aphasia

Exclusion Criteria

• preexisting neurological condition

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 80 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

VA Office of Research and Development

FED

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Diane L. Kendall, PhD

Role: PRINCIPAL_INVESTIGATOR

VA Puget Sound Health Care System Seattle Division, Seattle, WA

Locations

VA Puget Sound Health Care System Seattle Division, Seattle, WA

Seattle, Washington, United States

Countries

United States

References

Kendall DL, Hunting Pompon R, Brookshire CE, Minkina I, Bislick L. An analysis of aphasic naming errors as an indicator of improved linguistic processing following phonomotor treatment. Am J Speech Lang Pathol. 2013 May;22(2):S240-9. doi: 10.1044/1058-0360(2012/12-0078).

Reference Type: RESULT

PMID: 23695900 (View on PubMed)

Other Identifiers

C6572-R

Identifier Type: -

Identifier Source: org_study_id