Trial Outcomes & Findings for Phonomotor Treatment of Word Retrieval Deficits in Individuals With Aphasia (NCT NCT01163461)

Results Overview

percent change in the number of untrained words spoken correctly

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

28 participants

Primary outcome timeframe

Baseline to one week post treatment termination and three months post treatment termination

Results posted on

2017-08-31

Participant milestones
Measure	Delayed Aphasia Therapy 14 individuals were randomized to received aphasia therapy following a 6-week control delay phase. Upon completion of the 6-week control phase, they received 60 hours of behavioral therapy	Immediate Aphasia Therapy 14 individuals were randomized to received 60 hours of aphasia therapy immediately following testing. (no delay)
Overall Study STARTED	14	14
Overall Study COMPLETED	14	14
Overall Study NOT COMPLETED	0	0

Withdrawal data not reported

Phonomotor Treatment of Word Retrieval Deficits in Individuals With Aphasia

Baseline characteristics by cohort
Measure	Behavioral Aphasia Therapy n=28 Participants Single group, open trail where 28 individuals with aphasia received 60 hours of therapy
Age, Continuous	56 years STANDARD_DEVIATION 15 • n=5 Participants
Sex: Female, Male Female	14 Participants n=5 Participants
Sex: Female, Male Male	14 Participants n=5 Participants

Timeframe: Baseline to one week post treatment termination and three months post treatment termination

percent change in the number of untrained words spoken correctly

Outcome measures
Measure	Behavioral Aphasia Therapy n=28 Participants Single group, open trail where 28 individuals with aphasia received 60 hours of therapy
Speech Production % change immediately post treatment	5.27 % change score of untrained real words Standard Deviation 8.09
Speech Production % change 3 months post treatment	5.28 % change score of untrained real words Standard Deviation 7.55

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

Adverse event data not reported

Other adverse events
Measure	Single Group Open Trial n=28 participants at risk 28 individuals were randomized to receive either immediate speech therapy, or delayed speech therapy (following a 6 week delay period to control for Hawthorne effects). All participants received 60 hours of speech therapy 2 hours/day, 5 days/week for 6 weeks. Language behaviors were testing before, after and 3 months later.
Social circumstances No adverse events	0.00% 0/28

VAMC Puget Sound

Phone: 206-762-1010