Assessment of Vertical Pattern in Correlation With Third Molar Inclusion : A 3D CBCT Analysis

NCT ID: NCT06320665

Last Updated: 2025-03-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

80 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-12-01

Study Completion Date

2025-09-30

Brief Summary

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The objective is to compare the sagittal and vertical skeletal parameters of patients with an impacted third molar.

Patients will be analyzed according to their skeletal characteristics: skeletal class (sagittal direction) and facial skeletal typology (vertical direction).

The inclusion characteristics of third molars will also be analyzed, to see the links between typology and inclusion. The principal hypothesis is no significant difference in third molar inclusion patterns in relation to skeletal divergence.

Detailed Description

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The study is a non-interventional (observational) research involving the human person, research on existing data (retrospective study) and samples dealing with dentofacial orthopedics.

This study analyzes third molar inclusion patterns in relation with the skeletal characteristics, sagittal and vertical typology.

This is a comparative retrospective study of radiographs in three dimensions before any orthodontic treatment. The patients studied are at Bacchetti CS stage 5 (adults), and the third molar must be at least at Nolla stage 6 of formation.

There is no control group but there are subgroups depending of the skeletal characterics.

Conditions

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Impacted Third Molar Tooth

Study Design

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Observational Model Type

OTHER

Study Time Perspective

RETROSPECTIVE

Study Groups

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Class I

Patient with class I occlusion, with at least one impacted third molar

Radiographic measurement

Intervention Type OTHER

Measurements taken on 3D radiographs, to assess third molar inclusion and skeletal typology (vertical and sagittal)

Class II

Patients with class II malocclusion, with at least one impacted third molar

Radiographic measurement

Intervention Type OTHER

Measurements taken on 3D radiographs, to assess third molar inclusion and skeletal typology (vertical and sagittal)

Class III

Patients with class III malocclusion, with at least one impacted third molar

Radiographic measurement

Intervention Type OTHER

Measurements taken on 3D radiographs, to assess third molar inclusion and skeletal typology (vertical and sagittal)

Interventions

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Radiographic measurement

Measurements taken on 3D radiographs, to assess third molar inclusion and skeletal typology (vertical and sagittal)

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* CMV stage 5 on lateral radiography (end of growth)
* at least one impacted third molar at minimum Nolla stage 6 development

Exclusion Criteria

* Previous maxillofacial trauma
* Growing patients
* Missing permanent tooth or early avulsion
* Dysplasia
* Dentofacial deformities
* Endocrinological pathologies with implications for maxillofacial growth
* Syndromes
* History of maxillofacial or orthognathic surgery
* History of orthodontic treatment
* Incomplete data
Minimum Eligible Age

15 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Central Hospital, Nancy, France

OTHER

Sponsor Role lead

Responsible Party

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VANDE VANNET Bart

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Bart VANDE VANNET, PhD

Role: STUDY_DIRECTOR

Central Hospital, Nancy, France

Locations

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Département d'Orthopédie dento-faciale

Nancy, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Bart VANDE VANNET, PhD

Role: CONTACT

+32496284339

Mathilde LAE

Role: CONTACT

+33781893850

Facility Contacts

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Mathilde Laé, intern

Role: primary

+ 33 7 81 8938 50

Bart Vande Vannet, professor

Role: backup

References

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Idris AM, Al-Mashraqi AA, Abidi NH, Vani NV, Elamin EI, Khubrani YH, Sh Alhazmi A, Alamir AH, Fageeh HN, Meshni AA, Mashyakhy MH, Makrami AM, Gareeb Alla Abdalla A, Jafer M. Third molar impaction in the Jazan Region: Evaluation of the prevalence and clinical presentation. Saudi Dent J. 2021 May;33(4):194-200. doi: 10.1016/j.sdentj.2020.02.004. Epub 2020 Mar 4.

Reference Type BACKGROUND
PMID: 34025081 (View on PubMed)

Costa MG, Pazzini CA, Pantuzo MC, Jorge ML, Marques LS. Is there justification for prophylactic extraction of third molars? A systematic review. Braz Oral Res. 2013 Mar-Apr;27(2):183-8.

Reference Type BACKGROUND
PMID: 23538430 (View on PubMed)

Hounsome J, Pilkington G, Mahon J, Boland A, Beale S, Kotas E, Renton T, Dickson R. Prophylactic removal of impacted mandibular third molars: a systematic review and economic evaluation. Health Technol Assess. 2020 Jun;24(30):1-116. doi: 10.3310/hta24300.

Reference Type BACKGROUND
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Tassoker M, Kok H, Sener S. Is There a Possible Association between Skeletal Face Types and Third Molar Impaction? A Retrospective Radiographic Study. Med Princ Pract. 2019;28(1):70-74. doi: 10.1159/000495005. Epub 2018 Oct 31.

Reference Type BACKGROUND
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Legovic M, Legovic I, Brumini G, Vandura I, Cabov T, Ovesnik M, Mestrovic S, Slaj M, Skrinjaric A. Correlation between the pattern of facial growth and the position of the mandibular third molar. J Oral Maxillofac Surg. 2008 Jun;66(6):1218-24. doi: 10.1016/j.joms.2007.12.013.

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Zamora N, Llamas JM, Cibrian R, Gandia JL, Paredes V. A study on the reproducibility of cephalometric landmarks when undertaking a three-dimensional (3D) cephalometric analysis. Med Oral Patol Oral Cir Bucal. 2012 Jul 1;17(4):e678-88. doi: 10.4317/medoral.17721.

Reference Type BACKGROUND
PMID: 22322503 (View on PubMed)

Li C, Teixeira H, Tanna N, Zheng Z, Chen SHY, Zou M, Chung CH. The Reliability of Two- and Three-Dimensional Cephalometric Measurements: A CBCT Study. Diagnostics (Basel). 2021 Dec 7;11(12):2292. doi: 10.3390/diagnostics11122292.

Reference Type BACKGROUND
PMID: 34943528 (View on PubMed)

Carter K, Worthington S. Predictors of Third Molar Impaction: A Systematic Review and Meta-analysis. J Dent Res. 2016 Mar;95(3):267-76. doi: 10.1177/0022034515615857. Epub 2015 Nov 11.

Reference Type BACKGROUND
PMID: 26561441 (View on PubMed)

Bin Rubaia'an MA, Neyaz A, Talic F, Alkhamis A, Alghabban A, Assari A. The Association Between Skeletal Facial Types and Third Molars Impaction in a Saudi Arabian Subpopulation: A CBCT Study. Clin Cosmet Investig Dent. 2023 Aug 15;15:143-156. doi: 10.2147/CCIDE.S419325. eCollection 2023.

Reference Type BACKGROUND
PMID: 37601239 (View on PubMed)

Baccetti T, Franchi L, McNamara JA Jr. An improved version of the cervical vertebral maturation (CVM) method for the assessment of mandibular growth. Angle Orthod. 2002 Aug;72(4):316-23. doi: 10.1043/0003-3219(2002)0722.0.CO;2.

Reference Type BACKGROUND
PMID: 12169031 (View on PubMed)

Hagg U, Taranger J. Dental emergence stages and the pubertal growth spurt. Acta Odontol Scand. 1981;39(5):295-306. doi: 10.3109/00016358109162293.

Reference Type BACKGROUND
PMID: 6950638 (View on PubMed)

Hasan KM, Sobhana CR, Rawat SK, Singh D, Mongia P, Fakhruddin A. Third molar impaction in different facial types and mandibular length: A cross-sectional study. Natl J Maxillofac Surg. 2021 Jan-Apr;12(1):83-87. doi: 10.4103/njms.NJMS_111_20. Epub 2021 Mar 16.

Reference Type BACKGROUND
PMID: 34188406 (View on PubMed)

Mollaoglu N, Cetiner S, Gungor K. Patterns of third molar impaction in a group of volunteers in Turkey. Clin Oral Investig. 2002 Jun;6(2):109-13. doi: 10.1007/s00784-001-0144-1.

Reference Type BACKGROUND
PMID: 12166710 (View on PubMed)

Jaron A, Trybek G. The Pattern of Mandibular Third Molar Impaction and Assessment of Surgery Difficulty: A Retrospective Study of Radiographs in East Baltic Population. Int J Environ Res Public Health. 2021 Jun 3;18(11):6016. doi: 10.3390/ijerph18116016.

Reference Type BACKGROUND
PMID: 34205078 (View on PubMed)

Hashemipour MA, Tahmasbi-Arashlow M, Fahimi-Hanzaei F. Incidence of impacted mandibular and maxillary third molars: a radiographic study in a Southeast Iran population. Med Oral Patol Oral Cir Bucal. 2013 Jan 1;18(1):e140-5. doi: 10.4317/medoral.18028.

Reference Type BACKGROUND
PMID: 23229243 (View on PubMed)

Ahmed M, Shaikh A, Fida M. Diagnostic validity of different cephalometric analyses for assessment of the sagittal skeletal pattern. Dental Press J Orthod. 2018 Sep-Oct;23(5):75-81. doi: 10.1590/2177-6709.23.5.075-081.oar.

Reference Type BACKGROUND
PMID: 30427496 (View on PubMed)

Other Identifiers

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2024PI003

Identifier Type: -

Identifier Source: org_study_id

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