Effects of Resisted Versus Balance Exercises on Cognitive And Motor Function In Patients With Mild Cognitive Impairment

NCT ID: NCT06308237

Last Updated: 2024-10-15

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 70 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2024-02-25
• Study Completion Date: 2024-07-10

Brief Summary

Mild cognitive impairment affects older adults and it includes memory and attentions deficits, and problem-solving difficulties in activities of daily living. Resisted exercises is considered a viable strategy to improve balance and motor function in older population. Balance exercises comprises proprioceptive, visual and motor learning to a larger degree and has positive effects on memory and spatial cognition and improves balance and motor function. This study aims to determine the effects of resisted and balance exercises on cognition and motor function in patients with mild cognitive impairment.

Detailed Description

This randomized clinical trial will be conducted at Aziz Bhatti Shaheed Teaching Hospital Gujrat in seven months after approval of synopsis. The sample size for this trial is 78 patients with MCI. The participants will be randomly allocated into two groups using Online Randomization tool. Group A will receive resisted exercises for 30 minutes and Group B will receive balance exercises for 30 minutes. Participants will receive 3 sessions on alternate days per week for 12 weeks.Montreal Cognitive Assessment (MoCA) and Computerized battery test will be used to assess cognitive impairment, Mini-besTest and Time Up and Go Test (TUG) for balance and motor function.Data will be entered and analysed by using SPSS 26 software.

Conditions

Mild Cognitive Impairment

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: SINGLE

Study Groups

GROUP A (RESISTED EXERCISES)

Group A will receive a session of resisted exercises for 30 minutes. Treatment session will be given for 3 days per week for 12 weeks. This resisted training exercise program consist of three phases: Warm-up phase (5 minutes, after Warm-Up phase 20 minutes resisted exercise training then cooling phase (5 minutes).

Group Type: EXPERIMENTAL

RESISTED EXERCISES

Intervention Type: OTHER

Patients will perform Chest plank for 30 seconds with 4 repetitions.

Then the Participants will perform these exercises for 1 minute each with 4 repetitions:

Wide grip lateral pull down , Lying triceps press, Sit up squats, Barbell curl each.

And will perform Thigh adduction for1 minute with 2 repititions.

GROUP B (BALANCE EXERCISES)

Group B will receive a session of Balance exercises for 30 minutes. Treatment session will be given for 3 days per week for 12 weeks. This balance exercise program consist of three phases:Warm-up phase (5 minutes), after Warm-Up phase, 20 minutes balance exercise training then cooling phase (5 minutes).

Group Type: EXPERIMENTAL

BALANCE EXERCISES

Intervention Type: OTHER

Static and dynamic balance exercises will include:

Patients will perform Arm abduction holding a half-kg dumbbell, Opposite arm and leg in a quadruped position, Walking in a tandem stance(forward and backward), Turning and bending to the sides in a standing position, Pass through obstacles in a spiral, for 2 minutes each.

Then they will perform throwing a medicine ball to investigator and back while trying to maintain balance, Tandem stance, Walking backwards, Two-leg bridge as well as single (2 repetitions), Leg bridge (raising the other leg), walking on the heel, performing rhythmic movements while stepping on a circular environment and balance board exercises, for 1 minute each.

And will Walk up and down the stairs for 3 minutes.

Interventions

RESISTED EXERCISES

Patients will perform Chest plank for 30 seconds with 4 repetitions.

Then the Participants will perform these exercises for 1 minute each with 4 repetitions:

Wide grip lateral pull down , Lying triceps press, Sit up squats, Barbell curl each.

And will perform Thigh adduction for1 minute with 2 repititions.

Intervention Type: OTHER

BALANCE EXERCISES

Static and dynamic balance exercises will include:

Patients will perform Arm abduction holding a half-kg dumbbell, Opposite arm and leg in a quadruped position, Walking in a tandem stance(forward and backward), Turning and bending to the sides in a standing position, Pass through obstacles in a spiral, for 2 minutes each.

Then they will perform throwing a medicine ball to investigator and back while trying to maintain balance, Tandem stance, Walking backwards, Two-leg bridge as well as single (2 repetitions), Leg bridge (raising the other leg), walking on the heel, performing rhythmic movements while stepping on a circular environment and balance board exercises, for 1 minute each.

And will Walk up and down the stairs for 3 minutes.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

1. Patients with Mild Cognitive Impairment. (Having score between 18 - 24) on MoCA.

2. Participants with Both Genders will be included .

3. The Age limit for the participants will be 60 to 75 years.

4. Patients having Independence of life (ability to walk independently without any walking aid).

Exclusion Criteria

1. Previous and current History Cardiovascular, neurological, psychiatric and motor disorders like (fractures, diagnosis of Osteoporosis)

2. Patients taking any medication for mild cognition.

3. Depressive symptoms, acute and chronic conditions that would preclude exercise, regular exercise (>30 min/day, >3days/week).

4. Patients having estrogen replacement therapy.

5. Simultaneous participation in other studies.

6. Regular physical activity (once a week during the last 3 months); physio therapeutic treatment in the last 3 months.

7. Diseases that promote incapacity; severe visual deficiency; recurrent vertigo; and uncontrolled systemic arterial hypertension.

• Minimum Eligible Age: 60 Years
• Maximum Eligible Age: 75 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Riphah International University

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Muhammad Kashif, Phd-PT

Role: STUDY_CHAIR

Riphah International University

Locations

Riphah International University

Lahore, Punjab Province, Pakistan

Countries

Pakistan

Other Identifiers

REC/RCR&AHS/23/0293

Identifier Type: -

Identifier Source: org_study_id