Effects of Traditional Moderate Intensity Training and High Intensity Interval Training in Polycystic Ovarian Syndrome

NCT ID: NCT06303219

Last Updated: 2024-09-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

44 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-11-23

Study Completion Date

2024-08-19

Brief Summary

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To determine the comparative effects of traditional moderate intensity training and high intensity interval training on Anxiety, fatigue and Quality of Life in females with polycystic ovarian syndrome

Detailed Description

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Conditions

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Polycystic Ovarian Syndrome

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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TRADITIONAL MODERATE INTENSITY TRAINING

Group Type EXPERIMENTAL

RADITIONAL MODERATE INTENSITY TRAINING

Intervention Type OTHER

It consists of patients who will receive High-intensity interval training, including running as well as walking at 80% to 95% HR peak. Which is monitored by a smart watch. Before starting treatment, it follows a 10-minute warm-up exercise which includes basic stretches (Quads, Hams, and calf muscles) with a 30-second hold of both legs and same exercise will be pursued for the cool-down period. This intervention will be performed 5 days per week for 4 weeks.

The total duration of this session will be 50 minutes

HIGH INTENSITY INTERVAL TRAINING

Group Type ACTIVE_COMPARATOR

HIGH INTENSITY INTERVAL TRAINING

Intervention Type OTHER

It consists of patients who will receive Moderate-intensity interval training, including running as well as walking at 60% HR peak. Which is monitored by a smart watch. Before starting treatment, it follows a 10-minute warm-up exercise which includes basic stretches (Quads, Hams, and calf muscles) with a 30-second hold of both legs and same exercise will be pursued for the cool-down period. This intervention will be performed 5 days per week for 4 weeks.

The total duration of this session will be 50 minutes (

Interventions

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RADITIONAL MODERATE INTENSITY TRAINING

It consists of patients who will receive High-intensity interval training, including running as well as walking at 80% to 95% HR peak. Which is monitored by a smart watch. Before starting treatment, it follows a 10-minute warm-up exercise which includes basic stretches (Quads, Hams, and calf muscles) with a 30-second hold of both legs and same exercise will be pursued for the cool-down period. This intervention will be performed 5 days per week for 4 weeks.

The total duration of this session will be 50 minutes

Intervention Type OTHER

HIGH INTENSITY INTERVAL TRAINING

It consists of patients who will receive Moderate-intensity interval training, including running as well as walking at 60% HR peak. Which is monitored by a smart watch. Before starting treatment, it follows a 10-minute warm-up exercise which includes basic stretches (Quads, Hams, and calf muscles) with a 30-second hold of both legs and same exercise will be pursued for the cool-down period. This intervention will be performed 5 days per week for 4 weeks.

The total duration of this session will be 50 minutes (

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Participants with BMI greater than 25kg/m2
* Oligo- or anovulation/irregular cycles i.e 35 days
* Married women
* Primary infertility
* A diagnosis of polycystic ovaries based on ultrasound results

Exclusion Criteria

* Use of psychiatric or psychotropic medications.
* Unresolved gynecological conditions i.e Cervical Dysplasia, Pelvic floor prolapse, Uterine Fibroids, Urinary Incontinence
* Diabetes, pregnancy, smoking, illness or injury that prevented or limited exercise performance and existing participation in regular physical activity
Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Riphah International University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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hina gul

Role: PRINCIPAL_INVESTIGATOR

Riphah International University

Locations

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Gynecological Department of Fatima Memorial Hospital

Lahore, , Pakistan

Site Status

Countries

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Pakistan

References

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Kite C, Lahart IM, Afzal I, Broom DR, Randeva H, Kyrou I, Brown JE. Exercise, or exercise and diet for the management of polycystic ovary syndrome: a systematic review and meta-analysis. Syst Rev. 2019 Feb 12;8(1):51. doi: 10.1186/s13643-019-0962-3.

Reference Type BACKGROUND
PMID: 30755271 (View on PubMed)

Teede HJ, Tay CT, Laven JJE, Dokras A, Moran LJ, Piltonen TT, Costello MF, Boivin J, Redman LM, Boyle JA, Norman RJ, Mousa A, Joham AE; International PCOS Network. Recommendations from the 2023 international evidence-based guideline for the assessment and management of polycystic ovary syndrome. Eur J Endocrinol. 2023 Aug 2;189(2):G43-G64. doi: 10.1093/ejendo/lvad096.

Reference Type BACKGROUND
PMID: 37580861 (View on PubMed)

Patten RK, Bourke M, McIlvenna LC, Moreno-Asso A, Woessner MN, Stepto NK, Parker A. Longitudinal affective response to high-intensity interval training and moderate-intensity continuous training in overweight women with polycystic ovary syndrome: A randomised trial. Psychol Sport Exerc. 2023 Jan;64:102325. doi: 10.1016/j.psychsport.2022.102325. Epub 2022 Oct 26.

Reference Type BACKGROUND
PMID: 37665810 (View on PubMed)

Patten RK, McIlvenna LC, Levinger I, Garnham AP, Shorakae S, Parker AG, McAinch AJ, Rodgers RJ, Hiam D, Moreno-Asso A, Stepto NK. High-intensity training elicits greater improvements in cardio-metabolic and reproductive outcomes than moderate-intensity training in women with polycystic ovary syndrome: a randomized clinical trial. Hum Reprod. 2022 May 3;37(5):1018-1029. doi: 10.1093/humrep/deac047.

Reference Type BACKGROUND
PMID: 35325125 (View on PubMed)

Kite C, Parkes E, Taylor SR, Davies RW, Lagojda L, Brown JE, Broom DR, Kyrou I, Randeva HS. Time to Load Up-Resistance Training Can Improve the Health of Women with Polycystic Ovary Syndrome (PCOS): A Scoping Review. Med Sci (Basel). 2022 Sep 22;10(4):53. doi: 10.3390/medsci10040053.

Reference Type BACKGROUND
PMID: 36278523 (View on PubMed)

Patel V, Menezes H, Menezes C, Bouwer S, Bostick-Smith CA, Speelman DL. Regular Mindful Yoga Practice as a Method to Improve Androgen Levels in Women With Polycystic Ovary Syndrome: A Randomized, Controlled Trial. J Am Osteopath Assoc. 2020 Apr 14. doi: 10.7556/jaoa.2020.050. Online ahead of print.

Reference Type BACKGROUND
PMID: 32285088 (View on PubMed)

Abdollahi L, Mirghafourvand M, Babapour JK, Mohammadi M. Effectiveness of cognitive-behavioral therapy (CBT) in improving the quality of life and psychological fatigue in women with polycystic ovarian syndrome: a randomized controlled clinical trial. J Psychosom Obstet Gynaecol. 2019 Dec;40(4):283-293. doi: 10.1080/0167482X.2018.1502265. Epub 2018 Sep 3.

Reference Type BACKGROUND
PMID: 30175648 (View on PubMed)

.Jakhar R, Sen ED, Rastogi P. Improvement In Health-Related Quality of Life in Polycystic Ovarian Syndrome: A Randomized Controlled Trial. Journal of Survey in Fisheries Sciences. 2023:382-8.

Reference Type BACKGROUND

Ashila A, Murugaraj T. Effect of High Intensity Interval Training on Body Mass Index, Plasma Glucose and Insulin Among Individuals with Polycystic Ovary Syndrome Living in the South Indian Coast. Journal of Coastal Life Medicine. 2023;11:2579-85

Reference Type BACKGROUND

Other Identifiers

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REC/RCR&AHS/23/0577

Identifier Type: -

Identifier Source: org_study_id

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