Aerobic Capacity and Physical Fitness Level of Adolescents With PCOS

NCT ID: NCT05246306

Last Updated: 2022-10-12

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 44 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2021-09-22
• Study Completion Date: 2022-09-21

Brief Summary

Polycystic Ovary Syndrome (PCOS) is associated with hyperandrogenism, hyperinsulinemia and insulin resistance starting in the perimenarchal period. Insulin resistance also increases the risk of developing glucose intolerance, type 2 diabetes, hypertension, dyslipidemia and cardiovascular disorders. Studies on adult women with PCOS show that their aerobic capacity is affected. Therefore, in this study; it was aimed to compare the physical and cardiovascular fitness levels of adolescent PCOS patients with healthy adolescents.

Detailed Description

Polycystic Ovary Syndrome (PCOS) is associated with hyperandrogenism, hyperinsulinemia and insulin resistance starting in the perimenarchal period. Insulin resistance also increases the risk of developing glucose intolerance, type 2 diabetes, hypertension, dyslipidemia and cardiovascular disorders. Studies on adult women with PCOS show that their aerobic capacity is affected. Therefore, in this study; it was aimed to compare the physical and cardiovascular fitness levels of adolescent PCOS patients with healthy adolescents.Total fat and muscle ratios will be measured with the bioelectrical impedance test (BIA) instrument for body composition evaluation of individuals in both groups. Body mass index (BMI), waist/hip and waist/height ratios will be recorded. The level of cardiovascular fitness will be evaluated with the PACER test, which is among the Fitness Gram Test Protocol. For physical fitness level, muscular strength parameter will be evaluated with hand dynamometer and knee extensor muscle strength, and muscular endurance parameter will be evaluated with sit-up and push-up tests. Participants' physical activities will be evaluated with the Adolescent Physical Activity Questionnaire (PAQ-A).The quality of life of individuals with PCOS will be evaluated with the Polycystic Ovary Syndrome Quality of Life-50 Scale.

Conditions

Polycystic Ovary Syndrome

Study Design

• Observational Model Type: CASE_CONTROL
• Study Time Perspective: CROSS_SECTIONAL

Study Groups

Healthy group

Healthy adolescents aged 14-24 who have not been diagnosed with any chronic disease

No interventions assigned to this group

Patient with PCOS group

Adolescents between the ages of 14-24 diagnosed with Polycystic Ovary Syndrome according to the Rotherdam criteria.

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• Being between the ages of 14-24,
• Collecting Polycystic Syndrome according to Rotherdam,
• Not having had Covid-19.

• Being a female adolescent between the ages of 14-24,
• Not having been diagnosed with any chronic disease,
• Adolescents with regular menstrual cycles,
• Not taking any medication known to affect hormone, lipid and carbohydrate metabolism,
• Not having clinical signs of hyperandrogenism,
• Not having had Covid-19.

Exclusion Criteria

• Not to be between the ages of 14-24,
• Not showing the symptoms of Polycystic Ovary Syndrome (PCOS),
• Having had Covid-19,
• Having a chronic disease diagnosed other than PCOS,
• Having cognitive impairment that will affect their cooperation with tests.

• Not to be between the ages of 14-24,
• Having a chronic disease,
• Having had Covid-19,
• Having cognitive impairment that will affect their cooperation with tests.

• Minimum Eligible Age: 14 Years
• Maximum Eligible Age: 24 Years
• Eligible Sex: FEMALE
• Accepts Healthy Volunteers: Yes

Sponsors

Dr. Sami Ulus Children's Hospital

OTHER

Sponsor Role: collaborator

Hacettepe University

OTHER

Sponsor Role: lead

Responsible Party

Ebru Calik Kutukcu

Associate Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Ebru Calik Kutukcu, PhD

Role: PRINCIPAL_INVESTIGATOR

Hacettepe University

Locations

Hacettepe University

Ankara, , Turkey (Türkiye)

Countries

Turkey (Türkiye)

Other Identifiers

GO 21/947

Identifier Type: -

Identifier Source: org_study_id