Aerobic Training With and Without Resistance Training in Polycystic Ovarian Syndrome

NCT ID: NCT06198348

Last Updated: 2024-04-19

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 22 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2023-03-15
• Study Completion Date: 2024-03-15

Brief Summary

Polycystic ovary syndrome (PCOS) characterized by a chronic disorder in ovulation along with hyperandrogenism has become one of the most common endocrine disorders in women of reproductive age with an estimated 5%-15% prevalence. It has the symptoms such as menstrual disorders, infertility, hyperandrogenism, obesity, hirsutism and acne. PCOS is linked to Psychological morbidities e.g. increased risk of stress, depression, low self-esteem, poor body image, and reduced health-related quality of life. Approximately 75% of people with PCOS have a fat accumulation in the central area of the body.

Detailed Description

A Randomized controlled trial will be conducted to determine the effects of Aerobic training with and without resistance training on the waist to hip ratio, QoL and menstrual dysfunction in polycystic ovarian syndrome. A sample size of 22 PCOS women's will be taken, Data will be collected from Jinnah Hospital Lahore by using PCOSQ and SF-36 questionnaire. A written consent form will be taken from participants meeting inclusion criteria and will be randomly allocated into two groups of equal members. One group undergoing aerobic with resistance exercise training i.e., the experimental group and other with aerobic exercise i.e., control group. The interventions will be provided for 30 mints for 3 days per week for 2 months. All participants in both groups will be evaluated before and after the treatment programs.

Conditions

Polycystic Ovary Syndrome

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

Aerobic Exercise (Control Group)

Group A will receive Aerobic exercise plan. The treatment will be given with the frequency of 3 times per week for 8 weeks. Treatment sessions will be of 30 minutes with short resting intervals

Group Type: OTHER

Aerobic Exercise

Intervention Type: OTHER

Treatment Protocol to Group A It consists of patients who will receive aerobic exercise sessions 3 times per week for 8 weeks. Every session will be of 30 minutes.

It will include warm up phase, active phase and cool down phase Warm-up phase:

In which each participant will walk at 80 m/min at for 5 min.

Active phase:

Brisk walking or treadmill:

In which each participant will perform brisk walking for 15 mints initially. After that gradually duration of brisk walking will increase.

Aerobic exercise with resistance training (Experimental Group)

Group B will receive aerobic and resistance exercise plan. The frequency of treatment will be as same as that of aerobic exercise program i.e. 3 times a week for 8 weeks. Treatment sessions will be of 45 minutes with short resting intervals

Group Type: EXPERIMENTAL

Aerobic Exercises with Resistance training

Intervention Type: OTHER

These groups will perform these exercises:

Aerobic exercise +resistance exercises Exercise

Session: 3 days per week Time of exercise session: 30-45 min

After following protocol of aerobic exercise as mentioned above the subjects will perform resistance exercises. These Exercises will perform:

1. Leg press (dual leg press):

Leg press targets the Glutes "Quadriceps or quads .but they also work your "Hamstrings".

2. Crunches:

Crunches Target the abdominal muscles specifically rectus abdominis and obliques.

3. Squats:

Squats targets the adductor muscles of the hip, glutes and rectus abdominis muscle Leg Extension

Total Exercise plan for 12 weeks:

1-2 weeks: Repitations: 10-15 times

No of sets: 1 set Resistance: minimum 3-4 weeks:

Repitations: 10-15 times

No of sets: 2 set Resistance: moderate 5-6 weeks:

Repitations: 15-16 times

No of sets: 2 set Resistance: moderate 7-8 weeks:

Repitations: 15-16 times No of sets: 2 set

Interventions

Aerobic Exercise

Treatment Protocol to Group A It consists of patients who will receive aerobic exercise sessions 3 times per week for 8 weeks. Every session will be of 30 minutes.

It will include warm up phase, active phase and cool down phase Warm-up phase:

In which each participant will walk at 80 m/min at for 5 min.

Active phase:

Brisk walking or treadmill:

In which each participant will perform brisk walking for 15 mints initially. After that gradually duration of brisk walking will increase.

Intervention Type: OTHER

Aerobic Exercises with Resistance training

These groups will perform these exercises:

Aerobic exercise +resistance exercises Exercise

Session: 3 days per week Time of exercise session: 30-45 min

After following protocol of aerobic exercise as mentioned above the subjects will perform resistance exercises. These Exercises will perform:

1. Leg press (dual leg press):

Leg press targets the Glutes "Quadriceps or quads .but they also work your "Hamstrings".

2. Crunches:

Crunches Target the abdominal muscles specifically rectus abdominis and obliques.

3. Squats:

Squats targets the adductor muscles of the hip, glutes and rectus abdominis muscle Leg Extension

Total Exercise plan for 12 weeks:

1-2 weeks: Repitations: 10-15 times

No of sets: 1 set Resistance: minimum 3-4 weeks:

Repitations: 10-15 times

No of sets: 2 set Resistance: moderate 5-6 weeks:

Repitations: 15-16 times

No of sets: 2 set Resistance: moderate 7-8 weeks:

Repitations: 15-16 times No of sets: 2 set

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Age 18-40yrs
• Waist to hip ratio >87(20)
• Women who are diagnosed according to Rotterdam criteria e.g. oligo/anovulation, hyperandrogenism, and polycystic ovaries.(21)
• Female who physically able to performs exercise

Exclusion Criteria

• Women who are smoking and using drugs for depression.
• Married women
• Women with other pathological conditions like diabetes and thyroid diseases.
• Females who are not able to perform resistant exercise

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 40 Years
• Eligible Sex: FEMALE
• Accepts Healthy Volunteers: No

Sponsors

Riphah International University

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Faiza Taufiq, PPDPT

Role: PRINCIPAL_INVESTIGATOR

Riphah International University, Senior Lecturer

Locations

Jinnah Hospital

Lahore, Punjab Province, Pakistan

Countries

Pakistan

Other Identifiers

S22C14G92023

Identifier Type: -

Identifier Source: org_study_id