This Research Study Examines the Effects of Cannabidiol-infused Candy on Reducing the Bacteria Causing Tooth Decay, When Comparing it to a Sugar Free Candy on Adults.

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-01-27

Study Completion Date

2023-02-11

Brief Summary

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The goal of this clinical trial is to compare the effect of CBD candy versus sugar free candy on reducing the number of bacteria causing tooth decay, in adults The main question is to see whether CBD have any effect on reducing the number of Streptococcus mutans, in the oral cavity the main bacteria causing tooth decay.

Participants will be randomly placed in a group, and assigned to take either CBD-infused lozenge (if in the experimental group) or a sugar-free candy (if in the control group) once a day for 15 days.

A sample of saliva will be collected and analyzed in a lab before and after consumption of the candy to see whether either product could reduce the harmful bacteria in the mouth.

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Detailed Description

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Conditions

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Tooth Decay

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

30 Participants were randomly assigned to groups A (experimental group)and B (Control group).

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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300 Nano mg CBD Candy

Group Type EXPERIMENTAL

CBD infused candy

Intervention Type DIETARY_SUPPLEMENT

300 Nano mg CBD Candy cherry flavor

Sugar free raspberry flavor candy

Group Type PLACEBO_COMPARATOR

Sugar free Candy

Intervention Type DIETARY_SUPPLEMENT

Raspberry flavored sugar free candy

Interventions

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CBD infused candy

300 Nano mg CBD Candy cherry flavor

Intervention Type DIETARY_SUPPLEMENT

Sugar free Candy

Raspberry flavored sugar free candy

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

Adults aged 18 years or older, that were not taking any antibiotics, using prescribed toothpaste or mouthwash, who were not experiencing any tooth ache or mouth sores, have not visited the dentist within the past 48 hours, who willingly signed a consent form agreed to participate and be available on specific dates set by investigators and followed the recommended regimen for 15 days were included in the study. The suggested regimen involved consuming one candy in the evening at approximately the same time, allowing it to dissolve in the mouth without crushing it. Furthermore, individuals who could abstain from alcohol consumption for at least 12 hours before saliva collection on day 1 and day 15 and refrain from food or drink (except water) for preferably 2 hours were also eligible to participate in this clinical trial.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes