Xylitol Chewing-gums: Concentration in Saliva and Antibacterial Effect
NCT ID: NCT03971981
Last Updated: 2019-06-03
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
32 participants
INTERVENTIONAL
2018-02-01
2019-05-28
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
PREVENTION
QUADRUPLE
Study Groups
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100% Xylitol
The study had a cross-over design: the first half of the sample used the chewing-gum with Xylitol as the only sweeteners (64.5% of chewing-gum weight) and the other half use the chewing-gum with Xylitol among the sweeteners (22% of chewing-gum weight), after a 7-days wash-out period, the two sub-groups inverted the chewing gums.
100% Xylitol Gum
Subjects were instructed to consume the gums as they normally would be consumed.
22% Xylitol
The study had a cross-over design: the first half of the sample used the chewing-gum with Xylitol as the only sweeteners (64.5% of chewing-gum weight) and the other half use the chewing-gum with Xylitol among the sweeteners (22% of chewing-gum weight), after a 7-days wash-out period, the two sub-groups inverted the chewing gums.
22% Xylitol Gum
Subjects were instructed to consume the gums as they normally would be consumed.
Interventions
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100% Xylitol Gum
Subjects were instructed to consume the gums as they normally would be consumed.
22% Xylitol Gum
Subjects were instructed to consume the gums as they normally would be consumed.
Eligibility Criteria
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Inclusion Criteria
* the absence of diseases that can alter the saliva secretion rate
* a stimulated saliva flow at least of 1 ml/min.
Exclusion Criteria
19 Years
26 Years
ALL
Yes
Sponsors
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University of Milan
OTHER
Università degli Studi di Sassari
OTHER
Responsible Party
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Guglielmo Campus
Professor of Public Health Dentistry
Principal Investigators
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Guglielmo Campus
Role: PRINCIPAL_INVESTIGATOR
Università degli Studi di Sassari
Locations
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Department of Surgery, Microsurgery and Medicine Sciences University of Sassari
Sassari, Sardinia, Italy
Countries
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Other Identifiers
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SS-15884-GC
Identifier Type: -
Identifier Source: org_study_id
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