Using Tissue-based Spatial Data to Understand How Obesity-related Tumor Metabolites Fuel Prostate Cancer Progression
NCT ID: NCT06292897
Last Updated: 2024-03-05
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
25 participants
OBSERVATIONAL
2023-03-20
2027-01-15
Brief Summary
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ii. Characterize the immune infiltrate in the prostate carcinoma of the aforementioned patients.
iii. Assess the association between intra-tumoral lactate accumulation (using LDHA and MCT-4 protein expression levels as readouts) and alterations in the tumor immune microenvironment and/or deregulation of relevant oncogenic pathways.
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Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
RETROSPECTIVE
Study Groups
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obese individuals [Body Mass Index (BMI) > 30 affected by prostate cancer
observational study
observational study
normal-weight individuals [18 < BMI < 25] affected by prostate cancer
No interventions assigned to this group
Interventions
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observational study
observational study
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
18 Years
MALE
No
Sponsors
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National Research Council
UNKNOWN
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
OTHER
Responsible Party
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Giancarlo Albo
associate professor
Locations
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IRCCS Cà Granda Ospedale Maggiore Policlinico Milano
Milan, , Italy
Countries
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Central Contacts
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Facility Contacts
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giancarlo albo, MD
Role: primary
Other Identifiers
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3312
Identifier Type: -
Identifier Source: org_study_id
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