Model of Predicting Biochemical Recurrence After Radical Prostate Cancer Based on Pre-treatment PSMA PET / MR Image Features

NCT ID: NCT06604377

Last Updated: 2024-09-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

203 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-11-01

Study Completion Date

2024-06-30

Brief Summary

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The purpose of this study is to investigate the predictive value of preoperative 18F-PSMA-1007 PET/MR in the predictive effect of biological recurrence (BCR) after radical prostatectomy (RP) for localized prostate cancer (PCa).

Detailed Description

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Construct a predictive model for biochemical recurrence (BCR) in patients after radical prostatectomy using imaging parameters from preoperative 18F-PSMA-1007 PET/MRI, and compare the predictive performance of this model with existing clinical models. Data from three centers will be collected, with datasets from two centers used as the training set for the selection of predictive factors and model construction, while the dataset from the remaining center will serve as the validation set to assess the predictive performance of the model for BCR after prostatectomy.

Conditions

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Prostate Cancer

Study Design

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Observational Model Type

OTHER

Study Time Perspective

RETROSPECTIVE

Study Groups

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Shanghai East Hospital, Tongji University School of Medicine

Patients diagnosed with prostate cancer undergoing PSMA PET/MR examination prior to surgery.

Observe

Intervention Type OTHER

Ruijin

Interventions

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Observe

Ruijin

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. Age ≥ 18 years
2. Histologically confirmed prostate cancer without other types of malignancy -

Exclusion Criteria

1.Surgery or endocrine therapy is performed prior to the examination

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Minimum Eligible Age

18 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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Ruijin Hospital

OTHER

Sponsor Role lead

Responsible Party

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Hu Jiajia

Head of Otolaryngology

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Ruijin Hospital affiliated to Shanghai Jiao Tong University of Medicine

Shanghai, , China

Site Status

Countries

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China

Other Identifiers

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RuijinH 2024-244

Identifier Type: -

Identifier Source: org_study_id

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