Prediction of the Risk of Biochemical Relapse After Radical Prostatectomy for Prostate Cancer Using Radomics on Pre-therapeutic MRI

NCT ID: NCT04063800

Last Updated: 2019-09-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

195 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-06-26

Study Completion Date

2018-08-28

Brief Summary

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With 50% of post-operative biochemical failure, efficient predictive models are needed to guide post-operative management.

Radiomic features are quantitative features extracted from medical imaging, supposed to be correlated with tumor heterogeneity.

We aim to build and test three predictive models (clinical, radiomic and combined models).

Detailed Description

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Conditions

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Prostatic Adenocarcinoma

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Age \> 18yo
* Patients underwent radical prostatectomy
* High-risk prostate cancers: at least 1 criteria (pt3a/pT3b/pT4, R1, Gleason score \> 7)

Exclusion Criteria

* No available pre-operative MRI
* No analyzable pre-operative MRI
* proof of lymph-node involvement (cN1/2 or pN1/2)
* post-operative PSA \> 0.04ng/mL
Minimum Eligible Age

18 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Brest

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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CHRU de Brest

Brest, Brittany Region, France

Site Status

Centre Hospitalier de Cornouaille

Quimper, Brittany Region, France

Site Status

Countries

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France

Other Identifiers

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PREBOP (29BRC18.0108)

Identifier Type: -

Identifier Source: org_study_id

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