Prediction of Lymph Node Invasion for Prostate Adenocarcinoma

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

400 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-01-01

Study Completion Date

2022-11-30

Brief Summary

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Despite lymph node involvement (LNI) being one of the main prognostic factors in patients with prostate cancer (PCa), pelvic lymph node irradiation remains debated, possibly due to an insufficient selection of patients. Significant advances in LNI risk modelling have been achieved with the addition of visual interpretation of magnetic resonance imaging (MRI) data, but it is likely that quantitative analysis could further improve prediction models. In this study, the investigators aimed to develop and internally validate a novel LNI risk prediction model based on radiomic features extracted from pre-operative multimodal MRI.

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Detailed Description

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Conditions

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Adenocarcinoma of the Prostate

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Absence of invaded lymph node after extensive lymph node dissection

No interventions assigned to this group

Presence of invaded lymph node after extensive lymph node dissection

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Histologically proven adenocarcinoma of the prostate treated by prostatectomy with extensive lymph node dissection
* Available pre-operative +/- PET choline