Comperasion the Postoperative Effect of Low Laser Therapy and Platelet Rich Fibrin on Mandibular Third Molar Surgery.

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-01-02

Study Completion Date

2024-02-07

Brief Summary

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The aim of this study was investigate the comparison of postoperative effects of low laser treatment and platelet-rich fibrin application on mandibular impacted third molar tooth extraction. The study included a total of 60 patients with impacted mandibular third molar. Patients were evaluated in 4 randomly separated groups. In group 1, PRF was applied to the tooth socket. In group 2, PRF was applied to the tooth socket combined with Low Laser Treatment extraorally to the extraction area for three days within surgery day In group 3, Low Laser Treatment was applied to the extraorally to the extraction area for three days within surgery day. In group 4 (control group), tradional osteomy was made. The outcome variables were pain, swelling, the number of analgesics taken, and trismus. These variables were also assessed based on first, second, third, and seventh days following the operation. All of the 4 groups patients were prescribed an 875/125 mg amoxicillin/clavulanic acid tablet twice daily for five days.

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Detailed Description

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Conditions

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Impacted Third Molar Tooth

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Group 1

platelet rich fibrin placed into the socket of the extraciton tooth + Augmentin 1gr tablet prescribed 2 times a day

Diagnoses

Intervention Type DIAGNOSTIC_TEST

All of the patients withstand a radiological examination, including panoramic radiography, and all were handled by the same surgeon and assistant.

traditional osteotomies

Intervention Type PROCEDURE

In all groups the flap incision was triangular in shape which avoids muscle involvement (Archer flap).

platelet rich fibrin

Intervention Type BIOLOGICAL

Platelet rich fibrin (PRF), is an example and popular procedure for accelerate healing of soft and hard tissue because of the presence of various growth factors.a blood sample was taken without anticoagulant in 10 mL glass-coated plastic tubes that were immediately centrifuged (Elektro-mag M415P) at 3,000 rpm for 10 min (approximately 400 g) (13). The platelet-poor plasma that accumulated at the top of the tubes was discarded.PRF was dissected approximately 2 mm below its contact point with the red corpuscles situated beneath, to include any remaining platelets that may have localized below the junction between the PRF and red corpuscles.

Antibiotics, Penicillin

Intervention Type DRUG

Antibiotics are prescribed for the patients.

Analgesic

Intervention Type DRUG

Analgesics are prescribed for the patients.

Group 2

platelet rich fibrin placed in to the socket of the extractraciton tooth combined with low laser treatment extraorally to the extraction area for three days within surgery day + Augmentin 1gr tablet prescribed 2 times a day

Diagnoses

Intervention Type DIAGNOSTIC_TEST

All of the patients withstand a radiological examination, including panoramic radiography, and all were handled by the same surgeon and assistant.

traditional osteotomies

Intervention Type PROCEDURE

In all groups the flap incision was triangular in shape which avoids muscle involvement (Archer flap).

platelet rich fibrin

Intervention Type BIOLOGICAL

Platelet rich fibrin (PRF), is an example and popular procedure for accelerate healing of soft and hard tissue because of the presence of various growth factors.a blood sample was taken without anticoagulant in 10 mL glass-coated plastic tubes that were immediately centrifuged (Elektro-mag M415P) at 3,000 rpm for 10 min (approximately 400 g) (13). The platelet-poor plasma that accumulated at the top of the tubes was discarded.PRF was dissected approximately 2 mm below its contact point with the red corpuscles situated beneath, to include any remaining platelets that may have localized below the junction between the PRF and red corpuscles.

Antibiotics, Penicillin

Intervention Type DRUG

Antibiotics are prescribed for the patients.

low laser therapy, bicure laser

Intervention Type DEVICE

There are studies in the literature that low-energy lasers have positive effects on the biological and biochemical processes of wound healing. Acceleration of local circulation, increase in cell proliferation and collagen synthesis are among the various effects of laser application. B Cure Dental Pro Laser application will be applied to the patient for the first 3 days. Low dose laser application will be applied to the angulus area, covering the surgical area for 8 minutes. Before this laser procedure, the patient will be asked to fill out a pain scale. This pain scale and the number of analgesics used will be monitored for 3 days.

Analgesic

Intervention Type DRUG

Analgesics are prescribed for the patients.

Group 3

Low Laser Treatment was applied to the extraorally to the extraction area for three days within surgery day + Augmentin 1gr tablet prescribed 2 times a day

Diagnoses

Intervention Type DIAGNOSTIC_TEST

All of the patients withstand a radiological examination, including panoramic radiography, and all were handled by the same surgeon and assistant.

traditional osteotomies

Intervention Type PROCEDURE

In all groups the flap incision was triangular in shape which avoids muscle involvement (Archer flap).

Antibiotics, Penicillin

Intervention Type DRUG

Antibiotics are prescribed for the patients.

low laser therapy, bicure laser

Intervention Type DEVICE

There are studies in the literature that low-energy lasers have positive effects on the biological and biochemical processes of wound healing. Acceleration of local circulation, increase in cell proliferation and collagen synthesis are among the various effects of laser application. B Cure Dental Pro Laser application will be applied to the patient for the first 3 days. Low dose laser application will be applied to the angulus area, covering the surgical area for 8 minutes. Before this laser procedure, the patient will be asked to fill out a pain scale. This pain scale and the number of analgesics used will be monitored for 3 days.

Analgesic

Intervention Type DRUG

Analgesics are prescribed for the patients.

Control group.

Tradional osteomy was made. + Augmentin 1gr tablet prescribed 2 times a day

Diagnoses

Intervention Type DIAGNOSTIC_TEST

All of the patients withstand a radiological examination, including panoramic radiography, and all were handled by the same surgeon and assistant.

traditional osteotomies

Intervention Type PROCEDURE

In all groups the flap incision was triangular in shape which avoids muscle involvement (Archer flap).

Antibiotics, Penicillin

Intervention Type DRUG

Antibiotics are prescribed for the patients.

Analgesic

Intervention Type DRUG

Analgesics are prescribed for the patients.

Interventions

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Diagnoses

All of the patients withstand a radiological examination, including panoramic radiography, and all were handled by the same surgeon and assistant.

Intervention Type DIAGNOSTIC_TEST

traditional osteotomies

In all groups the flap incision was triangular in shape which avoids muscle involvement (Archer flap).

Intervention Type PROCEDURE

platelet rich fibrin

Platelet rich fibrin (PRF), is an example and popular procedure for accelerate healing of soft and hard tissue because of the presence of various growth factors.a blood sample was taken without anticoagulant in 10 mL glass-coated plastic tubes that were immediately centrifuged (Elektro-mag M415P) at 3,000 rpm for 10 min (approximately 400 g) (13). The platelet-poor plasma that accumulated at the top of the tubes was discarded.PRF was dissected approximately 2 mm below its contact point with the red corpuscles situated beneath, to include any remaining platelets that may have localized below the junction between the PRF and red corpuscles.

Intervention Type BIOLOGICAL

Antibiotics, Penicillin

Antibiotics are prescribed for the patients.

Intervention Type DRUG

low laser therapy, bicure laser

There are studies in the literature that low-energy lasers have positive effects on the biological and biochemical processes of wound healing. Acceleration of local circulation, increase in cell proliferation and collagen synthesis are among the various effects of laser application. B Cure Dental Pro Laser application will be applied to the patient for the first 3 days. Low dose laser application will be applied to the angulus area, covering the surgical area for 8 minutes. Before this laser procedure, the patient will be asked to fill out a pain scale. This pain scale and the number of analgesics used will be monitored for 3 days.

Intervention Type DEVICE

Analgesic

Analgesics are prescribed for the patients.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* The patient had no systemic diseases, no taken opioids for a long period, no current infections or acute pericoronitis, no smoke or drink alcohol, no pregnancy, the absence of allergy to penicillin and presence of penicillin allergy.