Effects of Low-level Laser Therapy on Soft and Hard Tissue Healing After Impacted Mandibular Third Molar Extraction

NCT ID: NCT07190950

Last Updated: 2025-11-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

22 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-08-30

Study Completion Date

2025-12-31

Brief Summary

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Impacted lower third molar extraction is one of the most commonly performed dental procedures in daily practice. However, this is considered a relatively invasive procedure. During the surgery, dental surgeon must reflect a full-thickness flap, remove bone to expose the tooth, section and deliver the tooth. As a result, after surgery, patients often experience many complications, from swelling, pain, jaw tightness, etc. to alveolar bone loss, periodontal problems distal to the second molar, etc.

Therefore, clinicians are always looking for additional therapies to minimize complications, helping patients have a more comfortable experience after wisdom tooth surgery.

To date, placing grafting materials such as bone or other biological materials (growth factors, platelet-rich plasma, platelet-rich fibrin) into the tooth socket has been shown to be able to preserve the alveolar crest after extraction. However, these materials require preparation time, are costly, and have the risk of infection related to bone grafts.

Meanwhile, low-level laser therapy (LLLT) is known as a safe, non-invasive therapy that can affect cell metabolism without causing tissue damage. This therapy has been widely applied in many fields of medicine in general and in dentistry in particular. Low-level lasers have been studied to help reduce swelling, pain, and jaw tightness after impacted lower wisdom teeth surgery. In vitro or in vivo studies evaluating the healing effect of low-level lasers have given very positive results. However, there is still a lack of scientific evidence to prove the healing effect of low-level lasers on human tooth extraction sockets.

The study we conducted is a scientific study, in the field of Dentistry. This study aimed to evaluate the effectiveness of low-level laser on soft tissue and bone healing after surgical extraction of impacted lower third molars in a group of Vietnamese population.

Detailed Description

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Conditions

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Third Molars Extraction Low Level Laser Therapy Bone Healing

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Control arm

After had third molar extraction at one side, patients do not receive low level laser therapy at this site (by not activating the tip)

Group Type NO_INTERVENTION

No interventions assigned to this group

Experiment arm

After had third molar extraction at the other side, patients receive 7 sessions of low level laser therapy at this side (the day of surgery, then first day, third day, seventh day, fourteenth day, twenty first day, twenty eighth day after surgery)

Group Type EXPERIMENTAL

Low Level Laser Therapy

Intervention Type PROCEDURE

Patients will receive LLLT at one side after third molar extraction surgery. There will be 7 sessions at the day of surgery, then first, third, seventh, fourteenth, twenty first, twenty eighth day after surgery.

Interventions

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Low Level Laser Therapy

Patients will receive LLLT at one side after third molar extraction surgery. There will be 7 sessions at the day of surgery, then first, third, seventh, fourteenth, twenty first, twenty eighth day after surgery.

Intervention Type PROCEDURE

Other Intervention Names

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LLLT

Eligibility Criteria

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Inclusion Criteria

* Healthy patients (at least 18 years of age) have both jaws lower impacted third molars indicated to be extracted. Both teeth are the same of

Exclusion Criteria

\-
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Medicine and Pharmacy at Ho Chi Minh City

OTHER

Sponsor Role lead

Responsible Party

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Nguyen Hoang Ngoc Hiep

DDS. Nguyen Hoang Ngoc Hiep

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Ly Thi Bich Nguyen, Doctor of Philosophy

Role: STUDY_DIRECTOR

Locations

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University of medicine and pharmacy at Ho Chi Minh city

Ho Chi Minh City, , Vietnam

Site Status RECRUITING

Countries

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Vietnam

Central Contacts

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Hiep Hoang Ngoc Nguyen, Doctor of Dental Surgery

Role: CONTACT

(+84) 848080298

Facility Contacts

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Hiep Hoang Ngoc Nguyen, Doctor of Dental Surgery

Role: primary

(+84) 848080298

Other Identifiers

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24368-ĐHYD

Identifier Type: -

Identifier Source: org_study_id

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