Conceptualisation of a Network Approach to Complete the Classification of Eating Disorders With the Aim of Better Personalising Their Management

NCT ID: NCT06252688

Last Updated: 2024-02-12

Basic Information

• Recruitment Status: NOT_YET_RECRUITING
• Clinical Phase: NA
• Total Enrollment: 840 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2024-02-15
• Study Completion Date: 2031-11-15

Brief Summary

Eating disorders (EDBs) are mental disorders with a great impact on the lives of individuals as well as a great cost imposed on society. The treatments currently available rely on different forms of psychotherapies with an unsatisfactory response rate as well as a considerable relapse rate . One of the reasons underlying the low success of available therapeutic modalities would be the heterogeneity of the clinical presentation of EDs, making their classification and the personalization of their treatment more difficult.The investigators hypothesize that a secondarily dimensional classification approach (respecting the categorical classification currently in use) of EDs based on the different dimensions disturbed in these disorders as well as in their comorbidities, would better represent their nosographic reality, which could provide patients with more personalized and potentially more effective care.

Detailed Description

Detailed Description:

The investigators will recruit a total of 840 patients with an eating disorder in the university hospital of Montpellier.

• Participation consists of a one-day visit with a multidisciplinary assessment. No action is specific to research except the biological collection for the constitution of a genetic bank. This is the usual management of patients with eating disorders addressed to our department.

Conditions

Eating Disorders; Eating Disorder Binge

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: OTHER
• Blinding Strategy: NONE

Study Groups

Participants

All participants performed the same evaluation: clinical and neuropsychological assessment.

All of them are patients with an eating disorder.

Group Type: OTHER

Ambulatory cares in a day-hospital (Lapeyronie, Montpellier) specialized in the evaluation of eating disorders.

Intervention Type: BEHAVIORAL

All patients assessed in the day-hospital will permormed the same evaluation :

• Blood sampling
• Calorimetry
• Osteodensotometry
• Psychiatric assement
• Endocrinologic assessment
• Dietetic assessment
• Neuropsychological assessment
• Self-questionnaires

With the patient agreement, a biological collection will be constituted. The objective is the subsequent study of biological factors involved in eating disorders (in particular genetic factors)

Interventions

Ambulatory cares in a day-hospital (Lapeyronie, Montpellier) specialized in the evaluation of eating disorders.

All patients assessed in the day-hospital will permormed the same evaluation :

• Blood sampling
• Calorimetry
• Osteodensotometry
• Psychiatric assement
• Endocrinologic assessment
• Dietetic assessment
• Neuropsychological assessment
• Self-questionnaires

With the patient agreement, a biological collection will be constituted. The objective is the subsequent study of biological factors involved in eating disorders (in particular genetic factors)

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• Patient with an eating disorder according to DSM-V criteria
• Patient aged from 15 to 65 years
• Patient who performs the day-hospital evaluation
• Patient affiliated to a French social security system
• Patient able to understand the nature, the aim and the methodology of the study
• For minor one of the legal guardians gave his consent

Exclusion Criteria

• Patient in an unstable somatic state (eg severe metabolic disorder making impossible or unreliable neuropsychological assessments)
• Patient's refusal to participate
• Patient protected by law (guardianship or curatorship)*
• Pregnant or nursing women. A dosage of βHCG will be performed to ensure the absence of pregnancy

• Minimum Eligible Age: 15 Years
• Maximum Eligible Age: 65 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

University Hospital, Montpellier

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Central Contacts

Sébastien GUILLAUME, PhD

Role: CONTACT

s-guillaume@chu-montpellier.fr

+33 4 67 33 82 89

Maude SENEQUE, MD

Role: CONTACT

m-senequehaize@chu-montpellier.fr

+33 0467335663

Other Identifiers

RECHMPL23_0261

Identifier Type: -

Identifier Source: org_study_id