Fluid Management Strategies on Blood Loss in Liver Transplantation
NCT ID: NCT06215404
Last Updated: 2025-04-11
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
60 participants
INTERVENTIONAL
2024-01-15
2025-12-31
Brief Summary
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The investigators plan to study different infusion goals and strategies in liver transplant surgery using a randomized group model, using the PiCCO (Pulse Contour Cardiac Output) cardiopulmonary volume monitor, and setting the stroke volume variation (SVV) as the macroscopic circulation.The purpose of this study was to divide it into restrictive and liberal groups to explore the impact on liver transplantation bleeding volume and inflammatory response as well as postoperative lung and renal function, and to collect statistics on clinical care and postoperative sequelae (pulmonary liver, renal function impairment, etc.) in order to develop the most appropriate infusion management strategy in liver transplantation.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
DOUBLE
Study Groups
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Liberal group
stroke volume variation \< 10%
Liberal group
Fluid challage to keep stroke volume variation \< 10%
restrictive group
stroke volume variation \< 18%
restrictive group
Fluid challage to keep stroke volume variation \< 18%
Interventions
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Liberal group
Fluid challage to keep stroke volume variation \< 10%
restrictive group
Fluid challage to keep stroke volume variation \< 18%
Eligibility Criteria
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Inclusion Criteria
* age between 18y/o to 75 y/o
* expected to recieve to receive liver transplantation
Exclusion Criteria
18 Years
75 Years
ALL
No
Sponsors
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National Taiwan University Hospital
OTHER
Responsible Party
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Principal Investigators
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Kuang-Cheng Chan, M.D.,PhD.
Role: PRINCIPAL_INVESTIGATOR
Department of Anesthesiology, National Taiwan University Hospital
Locations
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National Taiwan University Hospital
Taipei, , Taiwan
Countries
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Central Contacts
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Facility Contacts
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Kuang-Cheng Chan
Role: primary
Other Identifiers
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202308015MINC
Identifier Type: -
Identifier Source: org_study_id
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